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Helping Patients Breathe Easier, Do More & Enjoy Life

Breakthrough Technology for Severe Emphysema

The Zephyr Valve delivers durable clinical benefits – without surgery and its associated risks.1-5

Patients experience:1-5

  • Improved health status
  • Improved lung function
  • Increased exercise capacity
  • Reduced breathlessness or dyspnea
  • Reduced gas trapping
  • Improved quality of life

GOLD’s evidence “A” rating affirms that endobronchial valves, like the Zephyr® Valve, are a viable, minimally–invasive treatment option for severe emphysema, a form of COPD.10


How It Works

See how the Zephyr Valve treatment is performed as a minimally invasive lung volume reduction procedure to reduce hyperinflation and gas trapping in patients with severe emphysema. The Zephyr Valve is the first endobronchial valve to receive approval from the FDA for patients with either heterogenous and homogeneous emphysema.


Selecting the Right Patient

Assess with Certainty. Treat with Confidence.

Pulmonx provides a comprehensive solution for identifying eligible patients, using tools to help physicians precisely identify:

  • Patients most likely to benefit from Zephyr Valve treatment
  • Target lobes for treatment, which could include upper and/or lower lobes

Durable Clinical Benefits for Patients1-5

  • Clinically-proven, safe and effective treatment for patients with severe emphysema
  • Consistent clinical findings across four randomized control trials

Change from Baseline1

LIBERATE - FEV1 - Percent Change - Gray Background | amCharts
*Intent to Treat

Change from Baseline1

LIBERATE - 6MWD - Change from Baseline - Gray | amCharts

Change from Baseline1

LIBERATE - SGRQ - Change from Baseline - Gray | amCharts

Patient Benefits & Risks

Patients treated with the Zephyr Valve compared to patients on medication alone were able to:1

  • Return to activities that were previously limited
  • Feel less shortness of breath
  • Walk longer distances
  • Have more energy
  • Feel more confident leaving their home

Complications of the Zephyr Endobronchial Valve treatment can include but are not limited to pneumothorax, worsening of COPD symptoms, hemoptysis, pneumonia, dyspnea and, in rare cases, death.

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