{"id":90874,"date":"2024-06-27T08:47:07","date_gmt":"2024-06-27T13:47:07","guid":{"rendered":"https:\/\/pulmonx.com\/clinical-study-summaries-2\/"},"modified":"2024-09-26T09:50:49","modified_gmt":"2024-09-26T14:50:49","slug":"clinical-study-summaries-2","status":"publish","type":"page","link":"https:\/\/pulmonx.com\/uk-en\/clinical-study-summaries-2\/","title":{"rendered":"Clinical Study Summaries"},"content":{"rendered":"<\/p>\n
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Clinical Study Summaries<\/h1> <\/div>\n<\/div>\n <\/div>\n <\/div>\n <\/div>\n
\n <\/span><\/span>
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\n \"Zephyr-Valve-Liberate-Clinical-Study\" \n <\/div>\n \n \n <\/div>\n\n
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FEV1<\/sub> Percent Change
from Baseline to 12 Months<\/h4>\n

\r\n\r\n\t\r\n\t\tLIBERATE - FEV1 - Percent Change - Gray Background | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" \/>\r\n\t\t\r\n\t\t<!-- amCharts javascript sources -->\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/amcharts.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/cdn.amcharts.com\/lib\/3\/serial.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/themes\/light.js\"><\/script>\r\n\t\t\r\n\r\n\t\t<!-- amCharts javascript code -->\r\n\t\t<script type=\"text\/javascript\">\r\n\t\t\tAmCharts.makeChart(\"liberate-percent-change-fev1-12months\",\r\n\t\t\t\t{\r\n \"hideCredits\": \"true\",\r\n\t\t\t\t\t\"type\": \"serial\",\r\n\t\t\t\t\t\"categoryField\": \"category\",\r\n\t\t\t\t\t\"autoMarginOffset\": 0,\r\n\t\t\t\t\t\"autoMargins\": false,\r\n\t\t\t\t\t\"marginBottom\": 75,\r\n\t\t\t\t\t\"marginLeft\": 75,\r\n\t\t\t\t\t\"marginTop\": 50,\r\n\t\t\t\t\t\"startDuration\": 2,\r\n\t\t\t\t\t\"startEffect\": \"easeOutSine\",\r\n\t\t\t\t\t\"fontFamily\": \"Arial\",\r\n\t\t\t\t\t\"fontSize\": 14,\r\n\t\t\t\t\t\"pathToImages\": \"http:\/\/cdn.amcharts.com\/lib\/3\/images\/\",\r\n\t\t\t\t\t\"theme\": \"light\",\r\n\t\t\t\t\t\"categoryAxis\": {\r\n\t\t\t\t\t\t\"classNameField\": \"\",\r\n\t\t\t\t\t\t\"gridPosition\": \"start\",\r\n\t\t\t\t\t\t\"axisThickness\": 0,\r\n\t\t\t\t\t\t\"boldLabels\": true,\r\n\t\t\t\t\t\t\"centerLabels\": true,\r\n\t\t\t\t\t\t\"fontSize\": 14,\r\n\t\t\t\t\t\t\"gridColor\": \"#FFFFFF\",\r\n\t\t\t\t\t\t\"tickLength\": 0,\r\n\t\t\t\t\t\t\"title\": \"12 Months\"\r\n\t\t\t\t\t},\r\n\t\t\t\t\t\"trendLines\": [],\r\n\t\t\t\t\t\"graphs\": [\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"accessibleLabel\": \"LIBERATE - FEV1 - ITT*: [[category]] [[Column Height]] \u00b1 [[STD]]\",\r\n\t\t\t\t\t\t\t\"balloonText\": \"FEV<sub>1<\/sub> - ITT*: <br>[[category]] [[Column Height]] \u00b1 [[STD]]\",\r\n\t\t\t\t\t\t\t\"colorField\": \"Color\",\r\n\t\t\t\t\t\t\t\"errorField\": \"column-4\",\r\n\t\t\t\t\t\t\t\"fillAlphas\": 1,\r\n\t\t\t\t\t\t\t\"id\": \"AmGraph-1\",\r\n\t\t\t\t\t\t\t\"labelText\": \"\",\r\n\t\t\t\t\t\t\t\"lineColor\": \" \",\r\n\t\t\t\t\t\t\t\"title\": \"IMPACT-FEV1- Observed Cases\",\r\n\t\t\t\t\t\t\t\"type\": \"column\",\r\n\t\t\t\t\t\t\t\"valueField\": \"Column Height\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"accessibleLabel\": \"LIBERATE - FEV1 - ITT*: [[category]] [[Column Height]] \u00b1 [[STD]]\",\r\n\t\t\t\t\t\t\t\"balloonText\": \"FEV<sub>1<\/sub> - ITT*: <br>[[category]] [[Column Height]] \u00b1 [[STD]]\",\r\n\t\t\t\t\t\t\t\"clustered\": false,\r\n\t\t\t\t\t\t\t\"columnWidth\": 0,\r\n\t\t\t\t\t\t\t\"dashLengthField\": \"column-2\",\r\n\t\t\t\t\t\t\t\"fillAlphas\": 1,\r\n\t\t\t\t\t\t\t\"fillColors\": \"#000000\",\r\n\t\t\t\t\t\t\t\"fixedColumnWidth\": 5,\r\n\t\t\t\t\t\t\t\"id\": \"AmGraph-2\",\r\n\t\t\t\t\t\t\t\"labelText\": \"\",\r\n\t\t\t\t\t\t\t\"lineAlpha\": 0,\r\n\t\t\t\t\t\t\t\"lineColor\": \"#000000\",\r\n\t\t\t\t\t\t\t\"lineThickness\": 12,\r\n\t\t\t\t\t\t\t\"negativeBase\": -1,\r\n\t\t\t\t\t\t\t\"negativeFillAlphas\": 0,\r\n\t\t\t\t\t\t\t\"negativeLineAlpha\": 0,\r\n\t\t\t\t\t\t\t\"openField\": \"column-2\",\r\n\t\t\t\t\t\t\t\"showBalloon\": false,\r\n\t\t\t\t\t\t\t\"title\": \"graph 2\",\r\n\t\t\t\t\t\t\t\"topRadius\": 0,\r\n\t\t\t\t\t\t\t\"type\": \"column\",\r\n\t\t\t\t\t\t\t\"valueField\": \"column-3\",\r\n\t\t\t\t\t\t\t\"visibleInLegend\": false\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t],\r\n\t\t\t\t\t\"guides\": [],\r\n\t\t\t\t\t\"valueAxes\": [\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"id\": \"ValueAxis-1\",\r\n\t\t\t\t\t\t\t\"maximum\": 25,\r\n\t\t\t\t\t\t\t\"minimum\": -10,\r\n\t\t\t\t\t\t\t\"gridCount\": 7,\r\n\t\t\t\t\t\t\t\"title\": \"Percent Change (%)\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t],\r\n\t\t\t\t\t\"allLabels\": [\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"id\": \"Label-1\",\r\n\t\t\t\t\t\t\t\"text\": \"(p<0.001)\",\r\n\t\t\t\t\t\t\t\"x\": \"70%\",\r\n\t\t\t\t\t\t\t\"y\": \"25%\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"bold\": true,\r\n\t\t\t\t\t\t\t\"id\": \"=17.96%\",\r\n\t\t\t\t\t\t\t\"text\": \"\u0394=17.96\",\r\n\t\t\t\t\t\t\t\"x\": \"70%\",\r\n\t\t\t\t\t\t\t\"y\": 54\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t],\r\n\t\t\t\t\t\"balloon\": {\r\n\t\t\t\t\t\t\"borderThickness\": 1\r\n\t\t\t\t\t},\r\n\t\t\t\t\t\"titles\": [],\r\n\t\t\t\t\t\"dataProvider\": [\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"Zephyr Valve<br>(n=128)\",\r\n\t\t\t\t\t\t\t\"column-2\": \"14.69\",\r\n\t\t\t\t\t\t\t\"column-3\": \"19.63\",\r\n\t\t\t\t\t\t\t\"Color\": \"#4f2d7f\",\r\n\t\t\t\t\t\t\t\"STD\": \"27.93\",\r\n\t\t\t\t\t\t\t\"Column Height\": \"17.16\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"Control<br>(n=62)\",\r\n\t\t\t\t\t\t\t\"column-2\": \"-4.22\",\r\n\t\t\t\t\t\t\t\"column-3\": \"2.62\",\r\n\t\t\t\t\t\t\t\"Color\": \"#3095b4\",\r\n\t\t\t\t\t\t\t\"STD\": \"26.94\",\r\n\t\t\t\t\t\t\t\"Column Height\": \"-0.8\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"liberate-percent-change-fev1-12months\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html><\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column tb-column col4-2 tb_n3q8254 last\">\n <!-- module text -->\n<div class=\"module module-text tb_g8ip671 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h3>Published in The American Journal of Respiratory and Critical Care Medicine<a href=\"https:\/\/pulmonx.com\/references\/\" target=\"_blank\" rel=\"noopener\"><sup>1<\/sup><br><\/a><\/h3>\n<blockquote>\n<p>The benefits are comparable to those seen with LVRS (lung volume reduction surgery) but with a reduction in post-procedure morbidity.\u201d<\/p>\n<\/blockquote>\n<ul>\n<li>Multicentre, multinational, randomised controlled trial<\/li>\n<li>Results out to 12 months<\/li>\n<li>Heterogeneous emphysema with little to no collateral ventilation<\/li>\n<li>Clinically meaningful and statistically significant benefits over current standard of care medical therapy<\/li>\n<li>Improvements in:\n<ul>\n<li>Lung function<\/li>\n<li>Exercise tolerance<\/li>\n<li>Dyspnea<\/li>\n<li>Quality of life<\/li>\n<\/ul>\n<\/li>\n<\/ul> <\/div>\n<\/div>\n<!-- \/module text --><!-- module buttons -->\n<div class=\"module module-buttons tb_0bkp315 buttons-horizontal solid large squared\" data-lazy=\"1\">\n <div class=\"module-buttons-item tf_in_flx\">\n <a href=\"\/uk-en\/the-liberate-study\/\" class=\"ui builder_button tf_in_flx tb_default_color\" >\n Learn More <\/a>\n <\/div>\n <\/div>\n<!-- \/module buttons -->\n <\/div>\n <\/div>\n <\/div>\n <div data-css_id=\"p4d0618\" data-lazy=\"1\" class=\"module_row themify_builder_row fullwidth tb_p4d0618 tf_w\">\n <div class=\"row_inner col_align_top tb_col_count_2 tf_box tf_rel\">\n <div data-lazy=\"1\" class=\"module_column tb-column col4-2 tb_bjip620 first\">\n <!-- module image -->\n<div class=\"module module-image tb_cv2v620 image-center tf_mw\" data-lazy=\"1\">\n <div class=\"image-wrap tf_rel tf_mw\">\n <img decoding=\"async\" src=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/Zephyr-Valve-Transform-Clinical-Study-450x217.png\" width=\"450\" height=\"217\" class=\"wp-post-image wp-image-111\" title=\"Zephyr-Valve-Transform-Clinical-Study\" alt=\"Zephyr-Valve-Transform-Clinical-Study\" srcset=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/Zephyr-Valve-Transform-Clinical-Study-450x217.png 450w, https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/Zephyr-Valve-Transform-Clinical-Study-300x145.png 300w, https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/Zephyr-Valve-Transform-Clinical-Study-768x371.png 768w, https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/Zephyr-Valve-Transform-Clinical-Study-500x241.png 500w, https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/Zephyr-Valve-Transform-Clinical-Study.png 800w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/> \n <\/div>\n <!-- \/image-wrap -->\n \n <\/div>\n<!-- \/module image --><!-- module divider -->\n<div class=\"module tf_mw module-divider tb_ju1a621 solid \" style=\"border-width: 0px;border-color: #ffffff;margin-top: 30px;margin-bottom: 8px;\" data-lazy=\"1\">\n <\/div>\n<!-- \/module divider -->\n<!-- module text -->\n<div class=\"module module-text tb_fv6d774 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h4 style=\"text-align: center\">FEV<sub>1<\/sub> Percent Change <br>from Baseline to 6 Months<\/h4>\n<p style=\"text-align: center\"><!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>TRANSFORM - FEV1 - Percent Change | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" \/>\r\n\t\t\r\n\t\t<!-- amCharts javascript sources -->\r\n\t\t<script type=\"text\/javascript\" 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\"\",\r\n\t\t\t\t\t\t\t\"lineColor\": \" \",\r\n\t\t\t\t\t\t\t\"title\": \"IMPACT-FEV1- Observed Cases\",\r\n\t\t\t\t\t\t\t\"type\": \"column\",\r\n\t\t\t\t\t\t\t\"valueField\": \"Column Height\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"accessibleLabel\": \"TRANSFORM - FEV1 - ITT*: [[category]] [[Column Height]] \u00b1 [[STD]]\",\r\n\t\t\t\t\t\t\t\"balloonText\": \"FEV<sub>1<\/sub> - ITT*: <br>[[category]] [[Column Height]] \u00b1 [[STD]]\",\r\n\t\t\t\t\t\t\t\"clustered\": false,\r\n\t\t\t\t\t\t\t\"columnWidth\": 0,\r\n\t\t\t\t\t\t\t\"dashLengthField\": \"column-2\",\r\n\t\t\t\t\t\t\t\"fillAlphas\": 1,\r\n\t\t\t\t\t\t\t\"fillColors\": \"#000000\",\r\n\t\t\t\t\t\t\t\"fixedColumnWidth\": 5,\r\n\t\t\t\t\t\t\t\"id\": \"AmGraph-2\",\r\n\t\t\t\t\t\t\t\"labelText\": \"\",\r\n\t\t\t\t\t\t\t\"lineAlpha\": 0,\r\n\t\t\t\t\t\t\t\"lineColor\": \"#000000\",\r\n\t\t\t\t\t\t\t\"lineThickness\": 12,\r\n\t\t\t\t\t\t\t\"negativeBase\": -1,\r\n\t\t\t\t\t\t\t\"negativeFillAlphas\": 0,\r\n\t\t\t\t\t\t\t\"negativeLineAlpha\": 0,\r\n\t\t\t\t\t\t\t\"openField\": \"column-2\",\r\n\t\t\t\t\t\t\t\"showBalloon\": false,\r\n\t\t\t\t\t\t\t\"title\": \"graph 2\",\r\n\t\t\t\t\t\t\t\"topRadius\": 0,\r\n\t\t\t\t\t\t\t\"type\": \"column\",\r\n\t\t\t\t\t\t\t\"valueField\": \"column-3\",\r\n\t\t\t\t\t\t\t\"visibleInLegend\": false\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t],\r\n\t\t\t\t\t\"guides\": [],\r\n\t\t\t\t\t\"valueAxes\": [\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"id\": \"ValueAxis-1\",\r\n\t\t\t\t\t\t\t\"maximum\": 25,\r\n\t\t\t\t\t\t\t\"minimum\": -15,\r\n\t\t\t\t\t\t\t\"gridCount\": 7,\r\n\t\t\t\t\t\t\t\"title\": \"Percent Change (%)\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t],\r\n\t\t\t\t\t\"allLabels\": [\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"id\": \"p<0.001\",\r\n\t\t\t\t\t\t\t\"size\": 14,\r\n\t\t\t\t\t\t\t\"text\": \"(p<0.001)\",\r\n\t\t\t\t\t\t\t\"x\": \"88%\",\r\n\t\t\t\t\t\t\t\"y\": \"19%\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"bold\": true,\r\n\t\t\t\t\t\t\t\"id\": \"=29.3%\",\r\n\t\t\t\t\t\t\t\"size\": 14,\r\n\t\t\t\t\t\t\t\"text\": \"\u0394=29.3%\",\r\n\t\t\t\t\t\t\t\"x\": \"88%\",\r\n\t\t\t\t\t\t\t\"y\": 57\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t],\r\n\t\t\t\t\t\"balloon\": {\r\n\t\t\t\t\t\t\"borderThickness\": 1\r\n\t\t\t\t\t},\r\n\t\t\t\t\t\"titles\": [],\r\n\t\t\t\t\t\"dataProvider\": [\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"Zephyr Valve<br>(n=65)\",\r\n\t\t\t\t\t\t\t\"column-2\": \"17.03\",\r\n\t\t\t\t\t\t\t\"column-3\": \"24.37\",\r\n\t\t\t\t\t\t\t\"Color\": \"#4f2d7f\",\r\n\t\t\t\t\t\t\t\"STD\": \"29.6\",\r\n\t\t\t\t\t\t\t\"Column Height\": \"20.7\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"Control<br>(n=32)\",\r\n\t\t\t\t\t\t\t\"column-2\": \"-10.12\",\r\n\t\t\t\t\t\t\t\"column-3\": \"-7.08\",\r\n\t\t\t\t\t\t\t\"Color\": \"#3095b4\",\r\n\t\t\t\t\t\t\t\"STD\": \"13.0\",\r\n\t\t\t\t\t\t\t\"Column Height\": \"-8.6\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"transform-fev1-percent-change-6months\" style=\"width: 100%; height: 400px; background-color: #E6E6E6;\" ><\/div>\r\n\t<\/body>\r\n<\/html><\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column tb-column col4-2 tb_o8cp619 last\">\n <!-- module text -->\n<div class=\"module module-text tb_cnsx620 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h3>Published in The American Journal of Respiratory and Critical Care Medicine<a href=\"https:\/\/pulmonx.com\/references\/\" target=\"_blank\" rel=\"noopener\"><sup>2<\/sup><br><\/a><\/h3>\n<blockquote>\n<p>Benefits are in line with those seen with LVRS (lung volume reduction surgery), and the consistent trial results, potential reduction in post-procedure morbidity, and reversibility of the procedure position Zephyr Valve treatment as a viable treatment option in those who remain symptomatic on maximal medical therapy.”<\/p>\n<\/blockquote>\n<ul>\n<li>Multicentre, multinational, randomised controlled trial<\/li>\n<li>Heterogeneous emphysema with little or no collateral ventilation<\/li>\n<li>Clinically meaningful and statistically significant benefits over current standard of care medical therapy<\/li>\n<li>Improvements in:\n<ul>\n<li>Lung function<\/li>\n<li>Exercise tolerance<\/li>\n<li>Dyspnea<\/li>\n<li>Quality of life<\/li>\n<\/ul>\n<\/li>\n<\/ul> <\/div>\n<\/div>\n<!-- \/module text --><!-- module buttons -->\n<div class=\"module module-buttons tb_vxgn620 buttons-horizontal solid large squared\" data-lazy=\"1\">\n <div class=\"module-buttons-item tf_in_flx\">\n <a href=\"\/uk-en\/transform-clinical-study\/\" class=\"ui builder_button tf_in_flx tb_default_color\" >\n Learn More <\/a>\n <\/div>\n <\/div>\n<!-- \/module buttons -->\n <\/div>\n <\/div>\n <\/div>\n <div data-css_id=\"seh6451\" data-lazy=\"1\" class=\"module_row themify_builder_row fullwidth tb_seh6451 tf_w\">\n <span class=\"tb_row_frame_wrap tf_overflow tf_abs\" data-lazy=\"1\"><span class=\"tb_row_frame tb_row_frame_top tf_abs tf_hide tf_overflow tf_w\"><\/span><\/span> <div class=\"row_inner col_align_top tb_col_count_2 tf_box tf_rel\">\n <div data-lazy=\"1\" class=\"module_column tb-column col4-2 tb_bozs453 first\">\n <!-- module image -->\n<div class=\"module module-image tb_nnj0454 image-center tf_mw\" data-lazy=\"1\">\n <div class=\"image-wrap tf_rel tf_mw\">\n <img decoding=\"async\" src=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/Zephyr-Valve-Impact-Clinical-Study-450x217.png\" width=\"450\" height=\"217\" class=\"wp-post-image wp-image-107\" title=\"Zephyr-Valve-Impact-Clinical-Study\" alt=\"Zephyr-Valve-Impact-Clinical-Study\" srcset=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/Zephyr-Valve-Impact-Clinical-Study-450x217.png 450w, https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/Zephyr-Valve-Impact-Clinical-Study-300x145.png 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- Gray Background | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" \/>\r\n\t\t\r\n\t\t<!-- amCharts javascript sources -->\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/amcharts.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/cdn.amcharts.com\/lib\/3\/serial.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/themes\/light.js\"><\/script>\r\n\t\t\r\n\r\n\t\t<!-- amCharts javascript code -->\r\n\t\t<script type=\"text\/javascript\">\r\n\t\t\tAmCharts.makeChart(\"impact-fev1-percent-change-baseline-6months\",\r\n\t\t\t\t{\r\n \"hideCredits\": \"true\",\r\n\t\t\t\t\t\"type\": \"serial\",\r\n\t\t\t\t\t\"categoryField\": \"category\",\r\n\t\t\t\t\t\"autoMarginOffset\": 0,\r\n\t\t\t\t\t\"autoMargins\": false,\r\n\t\t\t\t\t\"marginBottom\": 75,\r\n\t\t\t\t\t\"marginLeft\": 75,\r\n\t\t\t\t\t\"marginTop\": 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\"(p<0.001)\",\r\n\t\t\t\t\t\t\t\"x\": \"70%\",\r\n\t\t\t\t\t\t\t\"y\": \"25%\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"bold\": true,\r\n\t\t\t\t\t\t\t\"id\": \"=16.27%\",\r\n\t\t\t\t\t\t\t\"text\": \"\u0394=16.27%\",\r\n\t\t\t\t\t\t\t\"x\": \"70%\",\r\n\t\t\t\t\t\t\t\"y\": 54\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t],\r\n\t\t\t\t\t\"balloon\": {\r\n\t\t\t\t\t\t\"borderThickness\": 1\r\n\t\t\t\t\t},\r\n\t\t\t\t\t\"titles\": [],\r\n\t\t\t\t\t\"dataProvider\": [\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"Zephyr Valve<br>(n=43)\",\r\n\t\t\t\t\t\t\t\"column-2\": \"7.18\",\r\n\t\t\t\t\t\t\t\"column-3\": \"15.90\",\r\n\t\t\t\t\t\t\t\"Color\": \"#4f2d7f\",\r\n\t\t\t\t\t\t\t\"STD\": \"28.58\",\r\n\t\t\t\t\t\t\t\"Column Height\": \"11.54\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"Control<br>(n=50)\",\r\n\t\t\t\t\t\t\t\"column-2\": \"-6.76\",\r\n\t\t\t\t\t\t\t\"column-3\": \"-2.70\",\r\n\t\t\t\t\t\t\t\"Color\": \"#3095b4\",\r\n\t\t\t\t\t\t\t\"STD\": \"14.38\",\r\n\t\t\t\t\t\t\t\"Column Height\": \"-4.73\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"impact-fev1-percent-change-baseline-6months\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html><\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column tb-column col4-2 tb_fmas454 last\">\n <!-- module text -->\n<div class=\"module module-text tb_kxrs455 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h3>Published in The American Journal of Respiratory and Critical Care Medicine<a href=\"https:\/\/pulmonx.com\/references\/\" target=\"_blank\" rel=\"noopener\"><sup>3<\/sup><br><\/a><\/h3>\n<blockquote>\n<p>EBV therapy in selected patients with homogeneous emphysema without collateral ventilation results in clinically meaningful benefits of improved lung function, exercise tolerance, and quality of life. Given the very limited treatment options available for this patient population, EBV therapy should be considered in these patients.\u201d<\/p>\n<\/blockquote>\n<ul>\n<li>Prospective randomised controlled trial<\/li>\n<li>Homogeneous emphysema with little or no collateral ventilation<\/li>\n<li>Clinically meaningful benefits in:\n<ul>\n<li>Lung function<\/li>\n<li>Exercise tolerance<\/li>\n<li>Quality of life<\/li>\n<\/ul>\n<\/li>\n<\/ul> <\/div>\n<\/div>\n<!-- \/module text --><!-- module buttons -->\n<div class=\"module module-buttons tb_q29u115 buttons-horizontal solid large squared\" data-lazy=\"1\">\n <div class=\"module-buttons-item tf_in_flx\">\n <a href=\"\/uk-en\/impact-clinical-study\/\" class=\"ui builder_button tf_in_flx tb_default_color\" >\n Learn More <\/a>\n <\/div>\n <\/div>\n<!-- \/module buttons -->\n <\/div>\n <\/div>\n <\/div>\n <div data-css_id=\"ixzy593\" data-lazy=\"1\" class=\"module_row themify_builder_row fullwidth tb_ixzy593 tf_w\">\n <div class=\"row_inner 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https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/Zephyr-Valve-Stelvio-Clinical-Study-500x241.png 500w, https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/Zephyr-Valve-Stelvio-Clinical-Study.png 800w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/> \n <\/div>\n <!-- \/image-wrap -->\n \n <\/div>\n<!-- \/module image --><!-- module divider -->\n<div class=\"module tf_mw module-divider tb_t4os189 solid \" style=\"border-width: 0px;border-color: #ffffff;margin-top: 30px;margin-bottom: 8px;\" data-lazy=\"1\">\n <\/div>\n<!-- \/module divider -->\n<!-- module text -->\n<div class=\"module module-text tb_sv2l393 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h4 style=\"text-align: center;\">FEV<sub>1<\/sub> Percent Change <br>from Baseline to 6 Months<\/h4>\n<p style=\"text-align: center;\"><!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>STELVIO - FEV1 - Percent Change - White Background | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using 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\"3.1\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"stelvio-percent-change-baseline-6months\" style=\"width: 100%; height: 400px; background-color: #E6E6E6;\" ><\/div>\r\n\t<\/body>\r\n<\/html><\/p>\n<h6>EMEA-EN-2322-v1<\/h6> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column tb-column col4-2 tb_8n37594 last\">\n <!-- module text -->\n<div class=\"module module-text tb_bo87302 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h3>Published in The New England Journal of Medicine<a href=\"https:\/\/pulmonx.com\/references\/\" target=\"_blank\" rel=\"noopener\"><sup>4<\/sup><br><\/a><\/h3>\n<blockquote>\n<p>Endobronchial valve treatment in patients with emphysema and a proven absence of interlobar collateral ventilation provided a measurable clinical benefit, with significantly improved lung function, exercise capacity, and quality of life as compared with usual care.”<\/p>\n<\/blockquote>\n<ul>\n<li>Prospective randomised controlled trial<\/li>\n<li>First randomised study to use Chartis<sup>\u00ae <\/sup> System to pre-select candidates<\/li>\n<li>Emphysema with little or no collateral ventilation<\/li>\n<li>Statistically and clinically greater improvements than the control group for:\n<ul>\n<li>Pulmonary function (FEV<sub>1<\/sub> and FVC)<\/li>\n<li>Exercise capacity<\/li>\n<li>Quality of life<\/li>\n<\/ul>\n<\/li>\n<li>One-year follow-up published in The American Journal of Respiratory and Critical Care Medicine<a href=\"https:\/\/pulmonx.com\/references\/\"><sup>5<\/sup><br><\/a><\/li>\n<\/ul>\n<p><a name=\"guidelines\"><\/a><\/p> <\/div>\n<\/div>\n<!-- \/module text --><!-- module buttons -->\n<div class=\"module module-buttons tb_a0u1552 buttons-horizontal solid large squared\" data-lazy=\"1\">\n <div class=\"module-buttons-item tf_in_flx\">\n <a href=\"\/uk-en\/stelvio-clinical-study\/\" class=\"ui builder_button tf_in_flx tb_default_color\" >\n Learn More <\/a>\n <\/div>\n <\/div>\n<!-- \/module buttons -->\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n<!--\/themify_builder_content-->","protected":false},"excerpt":{"rendered":"Clinical Study Summaries FEV1 Percent Changefrom Baseline to 12 Months LIBERATE - FEV1 - Percent Change - Gray Background | amCharts Published in The American Journal of Respiratory and Critical Care Medicine1 The benefits are comparable to those seen with LVRS (lung volume reduction surgery) but with a reduction in post-procedure morbidity.\u201d Multicentre, multinational, randomised [...]","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-90874","page","type-page","status-publish","hentry","has-post-title","has-post-date","has-post-category","has-post-tag","has-post-comment","has-post-author",""],"acf":[],"yoast_head":"<!-- This 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