Interventional Pulmonology Products

Enabling better breathing and improving quality of life. The Zephyr® valve is a one-way valve that blocks airflow to the diseased region of the lung to allow healthy regions to expand and function more efficiently.

Simple Implant Procedure

  • Clear mechanism of action
  • Can be easily removed, if needed

Effective and Predictable Outcomes – A Decade of Real-Life Experience

  • The broadest clinical experience of any minimally invasive emphysema treatment
  • Decade of clinical experience with more than 25,000 valves implanted
  • Over 110 publications documenting the safety, efficacy and long-term survival benefits for patients treated with severe emphysema1

Sustained and Meaningful Patient Benefits

Patients experience a significant improvement in lung function, exercise tolerance, and quality of life, as well as long-term survival benefits

  • Significantly improved FEV1 and sustained functional outcomes1,2,3,4,5
  • Clinically significant improvement in exercise tolerance5
  • Long-term survival benefit through five years1,2

1 Hopkinson NS et al. (2011) Eur Respir J
2 Venuta F et al. (2012) Eur Respir J;
3 Slebos DJ et al (2014): Thorax;
4 Iftikhar, H. (2014) Intl. J of COPD;
5 Wan IY (2006), Chest

How It Works

Image of endobronchial valves
Using a standard bronchoscope, Zephyr valves are delivered to target airways using a flexible delivery catheter
Image of one-way valve

Once implanted, the one-way valve prevents airflow into the diseased region, while allowing trapped air and fluids to escape


Image of a Lung

Reducing the volume of the diseased region may allow healthier regions to expand and function more efficiently


The Zephyr® endobronchial delivery catheter enables efficient and controlled delivery of the Zephyr valve

  • Proper valve sizing: The diameter gauges allow for a quick visual measurement of the bronchial diameter
  • Accurate positioning: A depth marker assists in positioning the catheter prior to valve deployment placement
  • Controlled delivery: An actuator lever facilitates precise deployment of the valve
Zephyr® Endobronchial Valve
Item Number Description Airway Diameter Range
EBV-TS-4.0 Zephyr® 4.0 Endobronchial Valve 4.0–7.0 mm
EBV-TS-4.0-LP Zephyr® 4.0-LP Endobronchial Valve 4.0–7.0 mm
EBV-TS-5.5 Zephyr® 5.5 Endobronchial Valve 5.5–8.5 mm
Zephyr Delivery Catheter
Item Number Description
EDC-TS-4.0 Zephyr® 4.0 Endobronchial Delivery Catheter
EDC-TS-4.0-J Zephyr® 4.0-J Endobronchial Delivery Catheter
EDC-TS-5.5 Zephyr® 5.5 Endobronchial Delivery Catheter

Note: Each catheter can be used to deploy up to four valves per patient