{"id":74926,"date":"2020-04-20T12:43:54","date_gmt":"2020-04-20T17:43:54","guid":{"rendered":"https:\/\/pulmonx.com\/stelvio-studio-clinico\/"},"modified":"2021-03-16T13:22:22","modified_gmt":"2021-03-16T18:22:22","slug":"stelvio-studio-clinico","status":"publish","type":"post","link":"https:\/\/pulmonx.com\/it\/stelvio-studio-clinico\/","title":{"rendered":"STELVIO Studio clinico"},"content":{"rendered":"\n
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\n \"PMX-Corporate-Website-Assets_ForTranslation-Italian-STELVIO-Logo\" \n <\/div>\n \n \n <\/div>\n\n
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\u201cIl trattamento con valvola endobronchiale nei pazienti affetti da enfisema e con dimostrata assenza di ventilazione collaterale interlobare \u00e8 risultato in benefici clinici misurabili, con un miglioramento significativo della funzione polmonare, della capacit\u00e0 di esercizio fisico e della qualit\u00e0 della vita rispetto allo standard di cura.\u201d4<\/sup><\/a><\/p>\n

\u00a0<\/p>\n<\/blockquote> <\/div>\n<\/div>\n\n

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\n \n Scarica il riepilogo dello studio <\/a>\n <\/div>\n <\/div>\n\n <\/div>\n
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Pubblicato su The New England Journal of Medicine4<\/a><\/sup><\/h1>\n

Il primo studio controllato randomizzato e prospettico relativo all\u2019uso di Chartis\u00ae<\/sup> nella selezione di candidati per il trattamento con valvola endobronchiale Zephyr.<\/p>\n

Metodi ed endpoint<\/b><\/h3>\n
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  • 68 pazienti con assenza di ventilazione collaterale (CV) confermata con il sistema Chartis\u00ae e probabili responder al trattamento con Zephyr\u00ae<\/sup>, randomizzati 1:1 al trattamento con valvola Zephyr o alla gestione medica.<\/li>\n
  • Gli indicatori di risultato primari sono stati le differenze tra i gruppi in quanto a variazione di FEV1<\/sub>, FVC e test del cammino di 6 minuti (6MWD) tra il valore basale e il valore a 6 mesi.<\/li>\n<\/ul> <\/div>\n<\/div>\n <\/div>\n <\/div>\n <\/div>\n
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    Disegno dello studio<\/h2> <\/div>\n<\/div>\n\n
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    * Lo studio STELVIO \u00e8 stato avviato e condotto da un medico indipendente. Pulmonx non \u00e8 stata coinvolta in alcuna parte dello studio.<\/p>\n <\/div>\n<\/div>\n\n

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    Risultati<\/h2> <\/div>\n<\/div>\n <\/div>\n <\/div>\n
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    Esito primario nella popolazione intent-to-treat<\/h4>\n

    Variazione media dal basale a 6 mesi<\/p> <\/div>\n<\/div>\n <\/div>\n

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    FEV1<\/sub><\/h5>\n

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class=\"column-4\">\u0394<\/td>\n<\/tr>\n<tr class=\"row-2\">\n\t<td class=\"column-1\">FEV<sub>1<\/sub><\/td><td class=\"column-2\">+20,9%<\/td><td class=\"column-3\">+3,1%<\/td><td class=\"column-4\">+17,8%<\/td>\n<\/tr>\n<tr class=\"row-3\">\n\t<td class=\"column-1\">FVC<\/td><td class=\"column-2\">+18,3%<\/td><td class=\"column-3\">+4,0%<\/td><td class=\"column-4\">+14,4%<\/td>\n<\/tr>\n<tr class=\"row-4\">\n\t<td class=\"column-1\">6MWD<\/td><td class=\"column-2\">+19,6%<\/td><td class=\"column-3\">-3,6%<\/td><td class=\"column-4\">+23,3%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <\/div>\n <div data-lazy=\"1\" class=\"module_subrow themify_builder_sub_row tf_w col_align_top tb_col_count_1 tb_ugio625\">\n <div data-lazy=\"1\" class=\"module_column sub_column col-full tb_9zfi627 first\">\n <!-- module text -->\n<div class=\"module module-text tb_06vg821 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h3>Benefici clinici sia per il sottogruppo con enfisema omogeneo sia per quello con enfisema eterogeneo<\/h3>\n<p>Esiti di efficacia per tutti i pazienti trattati con valvola Zephyr che hanno portato a termine lo studio. Variazione media dal basale.<\/p> <\/div>\n<\/div>\n<!-- \/module text --><!-- module text -->\n<div class=\"module module-text tb_f26i346 hide-tablet hide-mobile\" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n \n<table id=\"tablepress-19\" class=\"tablepress tablepress-id-19 stelvio\">\n<tbody class=\"row-striping\">\n<tr class=\"row-1\">\n\t<td class=\"column-1\"><\/td><td class=\"column-2\">Enfisema omogeneo (n=29)<\/td><td class=\"column-3\">Enfisema eterogeneo (n=22)<\/td>\n<\/tr>\n<tr class=\"row-2\">\n\t<td class=\"column-1\">FEV<sub>1<\/sub> (%)<\/td><td class=\"column-2\">+20,1<\/td><td class=\"column-3\">+32,6<\/td>\n<\/tr>\n<tr class=\"row-3\">\n\t<td class=\"column-1\">RV (%)<\/td><td class=\"column-2\">-16,3<\/td><td class=\"column-3\">-16,6<\/td>\n<\/tr>\n<tr class=\"row-4\">\n\t<td class=\"column-1\">6MWD (metri)<\/td><td class=\"column-2\">+69<\/td><td class=\"column-3\">+72<\/td>\n<\/tr>\n<tr class=\"row-5\">\n\t<td class=\"column-1\">SGRQ (punti)<\/td><td class=\"column-2\">-13<\/td><td class=\"column-3\">-19<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n <\/div>\n<\/div>\n<!-- \/module text --><!-- module image -->\n<div class=\"module module-image tb_9gtj639 image-center tf_mw hide-desktop hide-tablet_landscape\" data-lazy=\"1\">\n <div class=\"image-wrap tf_rel tf_mw\">\n <img decoding=\"async\" width=\"880\" height=\"262\" src=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/04\/STELVIO-Studio-Clinico-Scrivania.jpg\" class=\"wp-post-image wp-image-75648\" title=\"STELVIO-Studio-Clinico-Scrivania\" alt=\"STELVIO-Studio-Clinico-Scrivania\" srcset=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/04\/STELVIO-Studio-Clinico-Scrivania.jpg 880w, https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/04\/STELVIO-Studio-Clinico-Scrivania-300x89.jpg 300w, https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/04\/STELVIO-Studio-Clinico-Scrivania-768x229.jpg 768w\" sizes=\"(max-width: 880px) 100vw, 880px\" \/> \n <\/div>\n <!-- \/image-wrap -->\n \n <\/div>\n<!-- \/module image --><!-- module text -->\n<div class=\"module module-text tb_xhsd472 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h3 class=\"p1\">Tassi di responder significativamente superiori osservati per i pazienti trattati con valvola Zephyr rispetto allo standard di cura.<\/h3>\n<p class=\"p2\">Risultati dei responder MCID tra i pazienti che hanno portato a termine lo studio.<\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <\/div>\n <div data-lazy=\"1\" class=\"module_subrow themify_builder_sub_row tf_w col_align_top tb_col_count_4 tb_ojvn222\">\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_akwx224 first\">\n <!-- module text -->\n<div class=\"module module-text tb_l2lp137 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <p class=\"p1\">Variazione nel FEV<span class=\"s1\"><sub>1<\/sub><\/span> <\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_gqfc225\">\n 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id=\"stelvio-italian-fev1-control\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html> <\/div>\n<\/div>\n<!-- \/module plain text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_pdv8225\">\n <!-- module text -->\n<div class=\"module module-text tb_uj4n492 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h5 style=\"text-align: center;\">Gruppo trattato con valvole Zephyr<br>n=25<\/h5> <\/div>\n<\/div>\n<!-- \/module text --><!-- module plain text -->\n<div class=\"module module-plain-text tb_nh4p308 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>STELVIO Study Page - Italian: STELVIO - FEV1 - Zephyr Valve | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" \/>\r\n\t\t\r\n\t\t<!-- amCharts javascript sources -->\r\n\t\t<script type=\"text\/javascript\" 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\"#4F2D7F\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"stelvio-italian-fev1-zephyr\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html> <\/div>\n<\/div>\n<!-- \/module plain text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_iloh334 last\">\n <!-- module text -->\n<div class=\"module module-text tb_as6s700 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h5 style=\"text-align: center;\">Gruppo passato al trattamento con valvole Zephyr<br>n=26<\/h5> <\/div>\n<\/div>\n<!-- \/module text --><!-- module plain text -->\n<div class=\"module module-plain-text tb_5293214 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>STELVIO Study Page - Italian: STELVIO - FEV1 - Crossover | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" 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\"\",\r\n\t\t\t\t\t\t\t\"column-1\": \"60.67\",\r\n\t\t\t\t\t\t\t\"Color\": \"#FF5C39\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"\",\r\n\t\t\t\t\t\t\t\"column-1\": \"95.24\",\r\n\t\t\t\t\t\t\t\"Color\": \"#FF5C39\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"stelvio-italian-fev1-crossover\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html> <\/div>\n<\/div>\n<!-- \/module plain text --> <\/div>\n <\/div>\n <div data-lazy=\"1\" class=\"module_subrow themify_builder_sub_row tf_w col_align_top tb_col_count_4 tb_3uxs997\">\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_uy3s998 first\">\n <!-- module text -->\n<div class=\"module module-text tb_7cpn999 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <p class=\"p1\">Variazione nel 6MWD<\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_x11u999\">\n <!-- module text -->\n<div class=\"module module-text tb_2si50 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h5 style=\"text-align: center;\">Gruppo di controllo<br>n=33<\/h5> <\/div>\n<\/div>\n<!-- \/module text --><!-- module plain text -->\n<div class=\"module module-plain-text tb_m63841 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>STELVIO Study Page - Italian: STELVIO - 6MWD - Control Group | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" \/>\r\n\t\t\r\n\t\t<!-- amCharts javascript sources -->\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/amcharts.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/cdn.amcharts.com\/lib\/3\/serial.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" 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style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html> <\/div>\n<\/div>\n<!-- \/module plain text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_xfsv0\">\n <!-- module text -->\n<div class=\"module module-text tb_kedb0 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h5 style=\"text-align: center;\">Gruppo trattato con valvole Zephyr<br>n=25<\/h5> <\/div>\n<\/div>\n<!-- \/module text --><!-- module plain text -->\n<div class=\"module module-plain-text tb_s7o4650 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>STELVIO Study Page - Italian: STELVIO - 6MWD - Zephyr Valve | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" \/>\r\n\t\t\r\n\t\t<!-- amCharts javascript sources -->\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/amcharts.js\"><\/script>\r\n\t\t<script 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center;\">Gruppo passato al trattamento con valvole Zephyr<br>n=26<\/h5> <\/div>\n<\/div>\n<!-- \/module text --><!-- module plain text -->\n<div class=\"module module-plain-text tb_aq8q777 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>STELVIO Study Page - Italian: STELVIO - 6MWD - Crossover | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" \/>\r\n\t\t\r\n\t\t<!-- amCharts javascript sources -->\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/amcharts.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/cdn.amcharts.com\/lib\/3\/serial.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/themes\/light.js\"><\/script>\r\n\t\t\r\n\r\n\t\t<!-- amCharts javascript code -->\r\n\t\t<script 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themify_builder_sub_row tf_w col_align_top tb_col_count_4 tb_4t40589\">\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_ouuy589 first\">\n <!-- module text -->\n<div class=\"module module-text tb_n5mf334 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <p class=\"p1\">Variazione nel punteggio del SGRQ<\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_ye4z590\">\n <!-- module text -->\n<div class=\"module module-text tb_jufa590 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h5 style=\"text-align: center;\">Gruppo di controllo<br>n=33<\/h5> <\/div>\n<\/div>\n<!-- \/module text --><!-- module plain text -->\n<div class=\"module module-plain-text tb_bgw7256 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>STELVIO STUDY - Italian: STELVIO - SGRQ - Control Group | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" \/>\r\n\t\t\r\n\t\t<!-- amCharts javascript sources -->\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/amcharts.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/cdn.amcharts.com\/lib\/3\/serial.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/themes\/light.js\"><\/script>\r\n\t\t\r\n\r\n\t\t<!-- amCharts javascript code -->\r\n\t\t<script type=\"text\/javascript\">\r\n\t\t\tAmCharts.makeChart(\"stelvio-italian-sgrq-control\",\r\n\t\t\t\t{\r\n \"hideCredits\": \"true\",\r\n\t\t\t\t\t\"type\": \"serial\",\r\n\t\t\t\t\t\"categoryField\": \"category\",\r\n\t\t\t\t\t\"autoMarginOffset\": 0,\r\n\t\t\t\t\t\"autoMargins\": false,\r\n\t\t\t\t\t\"marginBottom\": 60,\r\n\t\t\t\t\t\"marginLeft\": 68,\r\n\t\t\t\t\t\"marginRight\": 95,\r\n\t\t\t\t\t\"marginTop\": 55,\r\n\t\t\t\t\t\"plotAreaFillColors\": \"\",\r\n\t\t\t\t\t\"startDuration\": 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id=\"stelvio-italian-sgrq-control\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html> <\/div>\n<\/div>\n<!-- \/module plain text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_5re9590\">\n <!-- module text -->\n<div class=\"module module-text tb_86n1590 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h5 style=\"text-align: center;\">Gruppo trattato con valvole Zephyr<br>n=25<\/h5> <\/div>\n<\/div>\n<!-- \/module text --><!-- module plain text -->\n<div class=\"module module-plain-text tb_0oto749 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>STELVIO STUDY - Italian: STELVIO - SGRQ - Zephyr Valve | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" \/>\r\n\t\t\r\n\t\t<!-- amCharts javascript sources -->\r\n\t\t<script type=\"text\/javascript\" 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\"#4F2D7F\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"stelvio-italian-sgrq-zephyr\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html> <\/div>\n<\/div>\n<!-- \/module plain text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_sty1592 last\">\n <!-- module text -->\n<div class=\"module module-text tb_pqjj592 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h5 style=\"text-align: center;\">Gruppo passato al trattamento con valvole Zephyr<br>n=26<\/h5> <\/div>\n<\/div>\n<!-- \/module text --><!-- module plain text -->\n<div class=\"module module-plain-text tb_ige8781 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>STELVIO STUDY - Italian: STELVIO - SGRQ - Crossover | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" 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\"#FF5C39\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"\",\r\n\t\t\t\t\t\t\t\"column-1\": \"-36.95\",\r\n\t\t\t\t\t\t\t\"Color\": \"#FF5C39\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"\",\r\n\t\t\t\t\t\t\t\"column-1\": \"-57.27\",\r\n\t\t\t\t\t\t\t\"Color\": \"#FF5C39\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"stelvio-italian-sgrq-crossover\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html> <\/div>\n<\/div>\n<!-- \/module plain text --> <\/div>\n <\/div>\n <div data-lazy=\"1\" class=\"module_subrow themify_builder_sub_row tf_w col_align_top tb_col_count_1 tb_kgi885\">\n <div data-lazy=\"1\" class=\"module_column sub_column col-full tb_gf5k87 first\">\n <!-- module divider -->\n<div class=\"module tf_mw module-divider tb_gb3g584 solid \" style=\"border-width: 1px;border-color: #3095b4;margin-top: 10px;margin-bottom: 40px;\" data-lazy=\"1\">\n <\/div>\n<!-- \/module divider -->\n<!-- module text -->\n<div class=\"module module-text tb_u6r8619 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h2 class=\"p1\">Conclusioni<\/h2>\n<p class=\"p1\">\u201cIl trattamento con valvola endobronchiale nei pazienti affetti da enfisema e con dimostrata assenza di ventilazione collaterale interlobare \u00e8 risultato in benefici clinici misurabili, con un miglioramento significativo della funzione polmonare, della capacit\u00e0 di esercizio fisico e della qualit\u00e0 della vita rispetto allo standard di cura.\u201d<\/p>\n<p>Le possibili complicazioni del trattamento con la valvola endobronchiale Zephyr includono, tra le altre, pneumotorace, peggioramento dei sintomi della BPCO, emottisi, polmonite, dispnea e, in rari casi, morte.<\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n<!--\/themify_builder_content-->","protected":false},"excerpt":{"rendered":"<p>Uno studio controllato randomizzato, multicentrico, multinazionale relativo alle valvole endobronchiali Zephyr\u00ae in pazienti con enfisema eterogeneo e ventilazione collaterale scarsa o assente.<\/p>\n","protected":false},"author":2,"featured_media":75629,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[59],"tags":[],"class_list":["post-74926","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-studio-clinico","has-post-title","has-post-date","has-post-category","has-post-tag","has-post-comment","has-post-author",""],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>STELVIO Studio clinico - Pulmonx<\/title>\n<meta name=\"robots\" content=\"index, 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