{"id":74918,"date":"2020-04-20T11:07:17","date_gmt":"2020-04-20T16:07:17","guid":{"rendered":"https:\/\/pulmonx.com\/impact-studio-clinico\/"},"modified":"2021-03-16T13:20:26","modified_gmt":"2021-03-16T18:20:26","slug":"impact-studio-clinico","status":"publish","type":"post","link":"https:\/\/pulmonx.com\/it\/impact-studio-clinico\/","title":{"rendered":"IMPACT Studio clinico"},"content":{"rendered":"\n
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\u201cIl trattamento con EBV (valvola endobronchiale) in pazienti selezionati affetti da enfisema omogeneo senza ventilazione collaterale produce benefici clinicamente significativi per la funzione polmonare, la tolleranza dell\u2019esercizio fisico e la qualit\u00e0 della vita. Considerate le limitate opzioni di trattamento disponibili per tale popolazione di pazienti, il trattamento con EBV deve essere preso in considerazione per questi pazienti.\u201d3<\/sup><\/a><\/p>\n<\/blockquote> <\/div>\n<\/div>\n\n

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\n \n Scarica il riepilogo dello studio <\/a>\n <\/div>\n <\/div>\n\n <\/div>\n
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Pubblicato su The American Journal of Respiratory and Critical Care Medicine3<\/a><\/sup><\/h1>\n

Il primo studio controllato randomizzato e prospettico relativo alle valvole endobronchiali Zephyr\u00ae<\/sup> in pazienti con enfisema omogeneo e ventilazione collaterale (CV) scarsa o assente.<\/p>\n

Metodi<\/h3>\n
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    93 pazienti affetti da enfisema omogeneo con assenza di ventilazione collaterale (CV) confermata con il sistema Chartis\u00ae<\/span><\/sup> e probabili responder al trattamento con valvola Zephyr, randomizzati 1:1 al trattamento con valvola Zephyr o alla gestione medica.<\/p>\n<\/li>\n

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    Per i pazienti trattati con valvola Zephyr, i lobi da trattare sono stati scelti in base ai punteggi di distruzione del tessuto causata dall\u2019enfisema e dalla riduzione della perfusione regionale, quindi sono stati occlusi completamente con le valvole.<\/p>\n<\/li>\n

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    Se i pazienti non hanno riscontrato benefici, il posizionamento delle valvole \u00e8 stato valutato a 30 giorni mediante TAC e, se necessario, la valvola \u00e8 stata rimossa e sostituita.<\/p>\n<\/li>\n<\/ul> <\/div>\n<\/div>\n <\/div>\n <\/div>\n <\/div>\n

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    Disegno dello studio<\/h2> <\/div>\n<\/div>\n\n
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    \n \"IMPACT-Study-Summary-Italian\" \n <\/div>\n \n \n <\/div>\n\n
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    Risultati<\/h2> <\/div>\n<\/div>\n
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    Esito primario nella popolazione intent-to-treat<\/h4>\n

    Variazione percentuale del FEV1<\/sub> dal basale a 3 mesi<\/p>\n

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\"29\",\r\n\t\t\t\t\t\t\t\"EBV close\": \"12\",\r\n\t\t\t\t\t\t\t\"Control High\": \".5\",\r\n\t\t\t\t\t\t\t\"Control low\": \"-14.7\",\r\n\t\t\t\t\t\t\t\"Control open\": \".5\",\r\n\t\t\t\t\t\t\t\"Control close\": \"-14.7\",\r\n\t\t\t\t\t\t\t\"Between Group Difference\": \"28.32\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"impact-italian-6mwd-line\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html><\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col3-1 tb_gqfc225\">\n <!-- module text -->\n<div class=\"module module-text tb_uj4n492 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h5 style=\"text-align: center;\">Variazione nel punteggio del SGRQ<\/h5>\n<p style=\"text-align: center;\"><!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>IMPACT Study Page - Italian: IMPACT - SGRQ - Line | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" \/>\r\n\t\t\r\n\t\t<!-- amCharts javascript sources -->\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/amcharts.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/cdn.amcharts.com\/lib\/3\/serial.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/themes\/light.js\"><\/script>\r\n\t\t\r\n\r\n\t\t<!-- amCharts javascript code -->\r\n\t\t<script type=\"text\/javascript\">\r\n\t\t\tAmCharts.makeChart(\"impact-italian-sgrq-line\",\r\n\t\t\t\t{\r\n \"hideCredits\": \"true\",\r\n\t\t\t\t\t\"type\": \"serial\",\r\n\t\t\t\t\t\"categoryField\": \"category\",\r\n\t\t\t\t\t\"autoMarginOffset\": 0,\r\n\t\t\t\t\t\"autoMargins\": false,\r\n\t\t\t\t\t\"marginBottom\": 32,\r\n\t\t\t\t\t\"marginLeft\": 75,\r\n\t\t\t\t\t\"marginTop\": 65,\r\n\t\t\t\t\t\"sequencedAnimation\": 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\"-7.47\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"impact-italian-sgrq-line\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html><\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col3-1 tb_pdv8225 last\">\n <!-- module text -->\n<div class=\"module module-text tb_as6s700 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h5 style=\"text-align: center;\">Variazione RV<\/h5>\n<p style=\"text-align: center;\"><!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>IMPACT Study Page - Italian: IMPACT - RV - Line | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" \/>\r\n\t\t\r\n\t\t<!-- amCharts javascript sources -->\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/amcharts.js\"><\/script>\r\n\t\t<script 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\"0\",\r\n\t\t\t\t\t\t\t\"EBV open\": \"0\",\r\n\t\t\t\t\t\t\t\"EBV close\": \"0\",\r\n\t\t\t\t\t\t\t\"Control High\": \"0\",\r\n\t\t\t\t\t\t\t\"Control low\": \"0\",\r\n\t\t\t\t\t\t\t\"Control open\": \"0\",\r\n\t\t\t\t\t\t\t\"Control close\": \"0\",\r\n\t\t\t\t\t\t\t\"Between Group Difference\": \"0\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"3 mesi\",\r\n\t\t\t\t\t\t\t\"EBV\": \"-420\",\r\n\t\t\t\t\t\t\t\"Control\": \"50\",\r\n\t\t\t\t\t\t\t\"EBV Candle High\": \"-280\",\r\n\t\t\t\t\t\t\t\"EBVCandle Low\": \"-560\",\r\n\t\t\t\t\t\t\t\"EBV open\": \"-280\",\r\n\t\t\t\t\t\t\t\"EBV close\": \"-560\",\r\n\t\t\t\t\t\t\t\"Control High\": \"175\",\r\n\t\t\t\t\t\t\t\"Control low\": \"-75\",\r\n\t\t\t\t\t\t\t\"Control open\": \"175\",\r\n\t\t\t\t\t\t\t\"Control close\": \"-75\",\r\n\t\t\t\t\t\t\t\"Between Group Difference\": \"-470\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"6 mesi\",\r\n\t\t\t\t\t\t\t\"EBV\": \"-480\",\r\n\t\t\t\t\t\t\t\"Control\": \"-60\",\r\n\t\t\t\t\t\t\t\"EBV Candle High\": \"-325\",\r\n\t\t\t\t\t\t\t\"EBVCandle Low\": \"-615\",\r\n\t\t\t\t\t\t\t\"EBV open\": \"-325\",\r\n\t\t\t\t\t\t\t\"EBV close\": \"-615\",\r\n\t\t\t\t\t\t\t\"Control High\": \"55\",\r\n\t\t\t\t\t\t\t\"Control low\": \"-180\",\r\n\t\t\t\t\t\t\t\"Control open\": \"55\",\r\n\t\t\t\t\t\t\t\"Control close\": \"-180\",\r\n\t\t\t\t\t\t\t\"Between Group Difference\": \"-420\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"impact-italian-rv-line\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html><\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <\/div>\n <div data-lazy=\"1\" class=\"module_subrow themify_builder_sub_row tf_w col_align_top tb_col_count_3 tb_hu6u780\">\n <div data-lazy=\"1\" class=\"module_column sub_column col3-1 tb_ik0q782 first\">\n <!-- module text -->\n<div class=\"module module-text tb_bftx782 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h5 style=\"text-align: center;\">Variazione nel FEV<sub>1<\/sub><\/h5>\n<p style=\"text-align: center;\"><!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>IMPACT Study Page - Italian: IMPACT - FEV1 - Line | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" \/>\r\n\t\t\r\n\t\t<!-- amCharts javascript sources -->\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/amcharts.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/cdn.amcharts.com\/lib\/3\/serial.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/themes\/light.js\"><\/script>\r\n\t\t\r\n\r\n\t\t<!-- amCharts javascript code -->\r\n\t\t<script type=\"text\/javascript\">\r\n\t\t\tAmCharts.makeChart(\"impact-italian-fev1-line\",\r\n\t\t\t\t{\r\n \"hideCredits\": 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0,\r\n\t\t\t\t\t\t\"boldLabels\": true,\r\n\t\t\t\t\t\t\"centerLabels\": true,\r\n\t\t\t\t\t\t\"fontSize\": 14,\r\n\t\t\t\t\t\t\"gridColor\": \"#FFFFFF\",\r\n\t\t\t\t\t\t\"tickLength\": 0,\r\n\t\t\t\t\t\t\"title\": \"\"\r\n\t\t\t\t\t},\r\n\t\t\t\t\t\"trendLines\": [],\r\n\t\t\t\t\t\"graphs\": [\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"accessibleLabel\": \"IMPACT - Variazione nel FEV1\",\r\n\t\t\t\t\t\t\t\"balloonText\": \"\",\r\n\t\t\t\t\t\t\t\"closeField\": \"EBV close\",\r\n\t\t\t\t\t\t\t\"clustered\": false,\r\n\t\t\t\t\t\t\t\"columnWidth\": 0,\r\n\t\t\t\t\t\t\t\"dashLengthField\": \"column-2\",\r\n\t\t\t\t\t\t\t\"fillAlphas\": 1,\r\n\t\t\t\t\t\t\t\"fillColors\": \"#000000\",\r\n\t\t\t\t\t\t\t\"fixedColumnWidth\": 2,\r\n\t\t\t\t\t\t\t\"highField\": \"EBV Candle High\",\r\n\t\t\t\t\t\t\t\"id\": \"AmGraph-2\",\r\n\t\t\t\t\t\t\t\"labelText\": \"\",\r\n\t\t\t\t\t\t\t\"lineAlpha\": 0,\r\n\t\t\t\t\t\t\t\"lineColor\": \"#FF5C39\",\r\n\t\t\t\t\t\t\t\"lowField\": \"EBVCandle Low\",\r\n\t\t\t\t\t\t\t\"minBulletSize\": 0,\r\n\t\t\t\t\t\t\t\"minDistance\": 0,\r\n\t\t\t\t\t\t\t\"negativeBase\": -1,\r\n\t\t\t\t\t\t\t\"negativeFillAlphas\": 0,\r\n\t\t\t\t\t\t\t\"negativeLineAlpha\": 0,\r\n\t\t\t\t\t\t\t\"openField\": \"EBV open\",\r\n\t\t\t\t\t\t\t\"showBalloon\": false,\r\n\t\t\t\t\t\t\t\"title\": \"graph 2\",\r\n\t\t\t\t\t\t\t\"topRadius\": 0,\r\n\t\t\t\t\t\t\t\"type\": \"candlestick\",\r\n\t\t\t\t\t\t\t\"valueField\": \"EBV close\",\r\n\t\t\t\t\t\t\t\"visibleInLegend\": false\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"accessibleLabel\": \"IMPACT - Variazione nel FEV1\",\r\n\t\t\t\t\t\t\t\"balloonText\": \"\",\r\n\t\t\t\t\t\t\t\"bullet\": \"square\",\r\n\t\t\t\t\t\t\t\"classNameField\": \"\",\r\n\t\t\t\t\t\t\t\"id\": \"EBV\",\r\n\t\t\t\t\t\t\t\"labelOffset\": 3,\r\n\t\t\t\t\t\t\t\"labelText\": \"\",\r\n\t\t\t\t\t\t\t\"legendAlpha\": 1,\r\n\t\t\t\t\t\t\t\"lineColor\": \"#4F2D7F\",\r\n\t\t\t\t\t\t\t\"lineThickness\": 3,\r\n\t\t\t\t\t\t\t\"markerType\": \"square\",\r\n\t\t\t\t\t\t\t\"showBalloon\": false,\r\n\t\t\t\t\t\t\t\"title\": \"Gruppo valvola Zephyr rispetto al basale\",\r\n\t\t\t\t\t\t\t\"valueField\": \"EBV\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"accessibleLabel\": \"IMPACT - Variazione nel FEV1\",\r\n\t\t\t\t\t\t\t\"balloonText\": \"\",\r\n\t\t\t\t\t\t\t\"bullet\": \"round\",\r\n\t\t\t\t\t\t\t\"dashLength\": 10,\r\n\t\t\t\t\t\t\t\"id\": \"Control\",\r\n\t\t\t\t\t\t\t\"lineColor\": \"#3095B4\",\r\n\t\t\t\t\t\t\t\"lineThickness\": 3,\r\n\t\t\t\t\t\t\t\"markerType\": \"circle\",\r\n\t\t\t\t\t\t\t\"showBalloon\": false,\r\n\t\t\t\t\t\t\t\"title\": \"Gruppo di controllo rispetto al basale\",\r\n\t\t\t\t\t\t\t\"valueField\": \"Control\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"accessibleLabel\": \"IMPACT - Variazione nel FEV1\",\r\n\t\t\t\t\t\t\t\"balloonText\": \"\",\r\n\t\t\t\t\t\t\t\"bulletBorderThickness\": 3,\r\n\t\t\t\t\t\t\t\"closeField\": \"Control close\",\r\n\t\t\t\t\t\t\t\"fillColors\": \"#000000\",\r\n\t\t\t\t\t\t\t\"fixedColumnWidth\": 1,\r\n\t\t\t\t\t\t\t\"highField\": \"Control High\",\r\n\t\t\t\t\t\t\t\"id\": \"AmGraph-4\",\r\n\t\t\t\t\t\t\t\"legendAlpha\": 0,\r\n\t\t\t\t\t\t\t\"lineColor\": \"#000000\",\r\n\t\t\t\t\t\t\t\"lowField\": \"Control low\",\r\n\t\t\t\t\t\t\t\"openField\": \"Control open\",\r\n\t\t\t\t\t\t\t\"showBalloon\": false,\r\n\t\t\t\t\t\t\t\"switchable\": false,\r\n\t\t\t\t\t\t\t\"title\": \"graph 4\",\r\n\t\t\t\t\t\t\t\"type\": \"candlestick\",\r\n\t\t\t\t\t\t\t\"valueField\": \"Control close\",\r\n\t\t\t\t\t\t\t\"visibleInLegend\": false\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"accessibleLabel\": \"IMPACT - Variazione nel FEV1\",\r\n\t\t\t\t\t\t\t\"balloonText\": \"\",\r\n\t\t\t\t\t\t\t\"bullet\": \"triangleUp\",\r\n\t\t\t\t\t\t\t\"dashLength\": 3,\r\n\t\t\t\t\t\t\t\"id\": \"AmGraph-5\",\r\n\t\t\t\t\t\t\t\"lineColor\": \"#FF5C39\",\r\n\t\t\t\t\t\t\t\"lineThickness\": 3,\r\n\t\t\t\t\t\t\t\"markerType\": \"triangleUp\",\r\n\t\t\t\t\t\t\t\"showBalloon\": false,\r\n\t\t\t\t\t\t\t\"title\": \"Differenza tra i gruppi\",\r\n\t\t\t\t\t\t\t\"valueField\": \"Between Group Difference\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t],\r\n\t\t\t\t\t\"guides\": [],\r\n\t\t\t\t\t\"valueAxes\": [\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"axisFrequency\": 2,\r\n\t\t\t\t\t\t\t\"id\": \"ValueAxis-1\",\r\n\t\t\t\t\t\t\t\"maximum\": 200,\r\n\t\t\t\t\t\t\t\"minimum\": -100,\r\n\t\t\t\t\t\t\t\"minMaxMultiplier\": 6,\r\n\t\t\t\t\t\t\t\"unit\": \"\",\r\n\t\t\t\t\t\t\t\"autoGridCount\": false,\r\n\t\t\t\t\t\t\t\"gridCount\": 8,\r\n\t\t\t\t\t\t\t\"minVerticalGap\": 39,\r\n\t\t\t\t\t\t\t\"title\": \"Millilitri (mL)\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t],\r\n\t\t\t\t\t\"allLabels\": [\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"id\": \"Label-1\",\r\n\t\t\t\t\t\t\t\"text\": \"p<0,001\",\r\n\t\t\t\t\t\t\t\"x\": \"76%\",\r\n\t\t\t\t\t\t\t\"y\": \"26%\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"id\": \"Label-2\",\r\n\t\t\t\t\t\t\t\"text\": \"p<0,001\",\r\n\t\t\t\t\t\t\t\"x\": \"50%\",\r\n\t\t\t\t\t\t\t\"y\": \"28%\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t],\r\n\t\t\t\t\t\"balloon\": {\r\n\t\t\t\t\t\t\"borderThickness\": 1\r\n\t\t\t\t\t},\r\n\t\t\t\t\t\"legend\": {\r\n\t\t\t\t\t\t\"enabled\": true,\r\n\t\t\t\t\t\t\"switchable\": false,\r\n\t\t\t\t\t\t\"tabIndex\": 8,\r\n\t\t\t\t\t\t\"valueAlign\": \"left\"\r\n\t\t\t\t\t},\r\n\t\t\t\t\t\"titles\": [],\r\n\t\t\t\t\t\"dataProvider\": [\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"Basale\",\r\n\t\t\t\t\t\t\t\"EBV\": \"0\",\r\n\t\t\t\t\t\t\t\"Control\": \"0\",\r\n\t\t\t\t\t\t\t\"EBV Candle High\": \"0\",\r\n\t\t\t\t\t\t\t\"EBVCandle Low\": \"0\",\r\n\t\t\t\t\t\t\t\"EBV open\": \"0\",\r\n\t\t\t\t\t\t\t\"EBV close\": \"0\",\r\n\t\t\t\t\t\t\t\"Control High\": \"0\",\r\n\t\t\t\t\t\t\t\"Control low\": \"0\",\r\n\t\t\t\t\t\t\t\"Control open\": \"0\",\r\n\t\t\t\t\t\t\t\"Control close\": \"0\",\r\n\t\t\t\t\t\t\t\"Between Group Difference\": \"0\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"3 mesi\",\r\n\t\t\t\t\t\t\t\"EBV\": \"100\",\r\n\t\t\t\t\t\t\t\"Control\": \"-20\",\r\n\t\t\t\t\t\t\t\"EBV Candle High\": \"130\",\r\n\t\t\t\t\t\t\t\"EBVCandle Low\": \"70\",\r\n\t\t\t\t\t\t\t\"EBV open\": \"130\",\r\n\t\t\t\t\t\t\t\"EBV close\": \"70\",\r\n\t\t\t\t\t\t\t\"Control High\": \"-5\",\r\n\t\t\t\t\t\t\t\"Control low\": \"-35\",\r\n\t\t\t\t\t\t\t\"Control open\": \"-5\",\r\n\t\t\t\t\t\t\t\"Control close\": \"-35\",\r\n\t\t\t\t\t\t\t\"Between Group Difference\": \"120\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"6 mesi\",\r\n\t\t\t\t\t\t\t\"EBV\": \"80\",\r\n\t\t\t\t\t\t\t\"Control\": \"-40\",\r\n\t\t\t\t\t\t\t\"EBV Candle High\": \"110\",\r\n\t\t\t\t\t\t\t\"EBVCandle Low\": \"53\",\r\n\t\t\t\t\t\t\t\"EBV open\": \"110\",\r\n\t\t\t\t\t\t\t\"EBV close\": \"53\",\r\n\t\t\t\t\t\t\t\"Control High\": \"-20\",\r\n\t\t\t\t\t\t\t\"Control low\": \"-60\",\r\n\t\t\t\t\t\t\t\"Control open\": \"-20\",\r\n\t\t\t\t\t\t\t\"Control close\": \"-60\",\r\n\t\t\t\t\t\t\t\"Between Group Difference\": \"120\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"impact-italian-fev1-line\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html><\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col3-1 tb_7z0s783\">\n <!-- module text -->\n<div class=\"module module-text tb_e6z3783 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h5 style=\"text-align: center;\">Variazione nel punteggio mMRC per la dispnea<\/h5>\n<p style=\"text-align: center;\"><!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>IMPACT Study Page - Italian: IMPACT - mMRC - Line | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" \/>\r\n\t\t\r\n\t\t<!-- amCharts javascript sources 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><\/div>\r\n\t<\/body>\r\n<\/html><\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col3-1 tb_akkw783 last\">\n <\/div>\n <\/div>\n <div data-lazy=\"1\" class=\"module_subrow themify_builder_sub_row tf_w col_align_top tb_col_count_1 tb_kgi885\">\n <div data-lazy=\"1\" class=\"module_column sub_column col-full tb_gf5k87 first\">\n <!-- module divider -->\n<div class=\"module tf_mw module-divider tb_gb3g584 solid \" style=\"border-width: 1px;border-color: #3095b4;margin-top: 10px;margin-bottom: 40px;\" data-lazy=\"1\">\n <\/div>\n<!-- \/module divider -->\n<!-- module text -->\n<div class=\"module module-text tb_u6r8619 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h2 class=\"p1\">Conclusioni<\/h2>\n<p class=\"p1\">I pazienti affetti da enfisema omogeneo possono ottenere benefici clinicamente significativi nella funzione polmonare, nella tolleranza all\u2019esercizio fisico e nella qualit\u00e0 della vita con il trattamento con valvola endobronchiale, quando vengono preselezionati per l\u2019assenza di ventilazione collaterale e quando presentano una occlusione lobare completa.<\/p> <\/div>\n<\/div>\n<!-- \/module text --><!-- module text -->\n<div class=\"module module-text tb_31w4199 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <p> <\/p>\n<p>Le possibili complicazioni del trattamento con la valvola endobronchiale Zephyr includono, tra le altre, pneumotorace, peggioramento dei sintomi della BPCO, emottisi, polmonite, dispnea e, in rari casi, morte.<\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n<!--\/themify_builder_content-->","protected":false},"excerpt":{"rendered":"<p>Uno studio controllato randomizzato, multicentrico, multinazionale relativo alle valvole endobronchiali Zephyr\u00ae in pazienti con enfisema eterogeneo e ventilazione collaterale scarsa o assente.<\/p>\n","protected":false},"author":2,"featured_media":75619,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[59],"tags":[],"class_list":["post-74918","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-studio-clinico","has-post-title","has-post-date","has-post-category","has-post-tag","has-post-comment","has-post-author",""],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>IMPACT Studio clinico - Pulmonx<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pulmonx.com\/it\/impact-studio-clinico\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta 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