{"id":75417,"date":"2020-04-27T10:40:25","date_gmt":"2020-04-27T15:40:25","guid":{"rendered":"https:\/\/pulmonx.com\/preuves-cliniques\/"},"modified":"2024-12-05T14:58:36","modified_gmt":"2024-12-05T19:58:36","slug":"preuves-cliniques","status":"publish","type":"page","link":"https:\/\/pulmonx.com\/fr\/preuves-cliniques\/","title":{"rendered":"Preuves cliniques"},"content":{"rendered":"<!--themify_builder_content-->\n<div id=\"themify_builder_content-75417\" data-postid=\"75417\" class=\"themify_builder_content themify_builder_content-75417 themify_builder tf_clear\">\n                    <div  data-parallax-bg=\"mobile\" data-css_id=\"a96fda5\" data-lazy=\"1\" class=\"module_row themify_builder_row fullwidth_row_container tb_a96fda5 tb_first tf_w wow\" data-tf-animation=\"fadeIn\">\n                        <div class=\"row_inner col_align_top tb_col_count_1 tf_box tf_rel\">\n                        <div  data-lazy=\"1\" class=\"module_column tb-column col-full tb_69d7692 first\">\n                            <\/div>\n                        <\/div>\n        <\/div>\n                        <div  data-lazy=\"1\" class=\"module_row themify_builder_row tb_104w755 tf_w\">\n                        <div class=\"row_inner col_align_top tb_col_count_1 tf_box tf_rel\">\n                        <div  data-lazy=\"1\" class=\"module_column tb-column col-full tb_udi9757 first\">\n                    <!-- module text -->\n<div  class=\"module module-text tb_knhn986   \" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <h1><strong>&gt;100 articles scientifiques publi\u00e9s <\/strong><\/h1>\n<p>Les r\u00e9sultats de plusieurs essais cliniques randomis\u00e9s portant sur la valve Zephyr<sup>\u00ae<\/sup> ont d\u00e9montr\u00e9 des avantages cliniquement significatifs en termes de fonction pulmonaire, de capacit\u00e9 \u00e0 faire de l\u2019exercice et de qualit\u00e9 de vie (QV)<a style=\"font-size: 15px;\" href=\"\/fr\/la-biographie\/\"><sup>1-5<\/sup><\/a><\/p>    <\/div>\n<\/div>\n<!-- \/module text --><!-- module image -->\n<div  class=\"module module-image tb_tetw383 image-center   tf_mw\" data-lazy=\"1\">\n        <div class=\"image-wrap tf_rel tf_mw\">\n            <img decoding=\"async\" src=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/07\/Staircase-French-01-1024x748-650x474.png\" width=\"650\" height=\"474\" class=\"wp-post-image wp-image-76615\" title=\"Staircase-French-01\" alt=\"Staircase-French-01\" srcset=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/07\/Staircase-French-01-1024x748-650x474.png 650w, https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/07\/Staircase-French-01-300x219.png 300w, https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/07\/Staircase-French-01-1024x748.png 1024w, https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/07\/Staircase-French-01-768x561.png 768w, https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/07\/Staircase-French-01-1536x1122.png 1536w, https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/07\/Staircase-French-01-2048x1495.png 2048w\" sizes=\"(max-width: 650px) 100vw, 650px\" \/>    \n        <\/div>\n    <!-- \/image-wrap -->\n    \n        <\/div>\n<!-- \/module image -->        <\/div>\n                        <\/div>\n        <\/div>\n                        <div  data-css_id=\"44409ab\" data-lazy=\"1\" class=\"module_row themify_builder_row fullwidth tb_44409ab tf_w\">\n                        <div class=\"row_inner col_align_top tb_col_count_1 tf_box tf_rel\">\n                        <div  data-lazy=\"1\" class=\"module_column tb-column col-full tb_f1af839 first\">\n                            <div  data-lazy=\"1\" class=\"module_subrow themify_builder_sub_row tf_w col_align_top tb_col_count_2 tb_doxp708\">\n                <div  data-lazy=\"1\" class=\"module_column sub_column col4-2 tb_dmq3710 first\">\n                    <!-- module text -->\n<div  class=\"module module-text tb_40up511   \" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <ul>\n<li>4 ECR publi\u00e9s sur l&rsquo;utilisation de la valve Zephyr et de Chartis<sup>\u00ae<\/sup> pour pr\u00e9s\u00e9lectionner les patients<a style=\"font-size: 15px;\" href=\"\/fr\/la-biographie\/\"><sup>1-5<\/sup><\/a><\/li>\n<li>Publi\u00e9s dans les revues New England Journal of Medicine, The Lancet et American Journal of Respiratory and Critical Care Medicine<a style=\"font-size: 15px;\" href=\"\/fr\/la-biographie\/\"><sup>1-5,16<\/sup><\/a><\/li>\n<\/ul>    <\/div>\n<\/div>\n<!-- \/module text -->        <\/div>\n                    <div  data-lazy=\"1\" class=\"module_column sub_column col4-2 tb_svbr710 last\">\n                    <!-- module text -->\n<div  class=\"module module-text tb_gaa0691   \" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <ul>\n<li>Am\u00e9liorations statistiquement et cliniquement significatives par rapport au traitement standard dans le cadre de plusieurs essais<a style=\"font-size: 15px;\" href=\"\/fr\/la-biographie\/\"><sup>1-4<\/sup><\/a><\/li>\n<li>Succ\u00e8s du traitement constat\u00e9 dans un large \u00e9ventail de crit\u00e8res d&rsquo;\u00e9valuation primaires et secondaires<a style=\"font-size: 15px;\" href=\"\/fr\/la-biographie\/\"><sup>1-5<\/sup><\/a><\/li>\n<\/ul>    <\/div>\n<\/div>\n<!-- \/module text -->        <\/div>\n                    <\/div>\n                <div  data-lazy=\"1\" class=\"module_subrow themify_builder_sub_row tf_w col_align_top tb_col_count_3 tb_5ih5585\">\n                <div  data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_xb5f586 first\">\n                            <\/div>\n                    <div  data-lazy=\"1\" class=\"module_column sub_column col4-2 tb_8h3x410\">\n                    <!-- module text -->\n<div  class=\"module module-text tb_yney128   \" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <h3 class=\"p1\" style=\"text-align: center;\">R\u00e9sultats cliniques constants dans quatre \u00e9tudes randomis\u00e9es et contr\u00f4l\u00e9es<\/h3>    <\/div>\n<\/div>\n<!-- \/module text --><!-- module text -->\n<div  class=\"module module-text tb_bm2b840    hide-tablet hide-mobile\" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        \n<table id=\"tablepress-20\" class=\"tablepress tablepress-id-20 studies tbody-has-connected-cells\">\n<tbody class=\"row-striping\">\n<tr class=\"row-1\">\n\t<td rowspan=\"2\" class=\"column-1\">\u00c9tude contr\u00f4l\u00e9e randomis\u00e9e<\/td><td rowspan=\"2\" class=\"column-2\">Plan d'\u00e9tude<\/td><td rowspan=\"2\" class=\"column-3\">Taille de l\u2019\u00e9chantillon et phase de suivi<\/td><td rowspan=\"2\" class=\"column-4\">R\u00e9ussite de la proc\u00e9dure (% RVPT)<\/td><td colspan=\"3\" class=\"column-5\">Diff\u00e9rence entre le groupe VEB et le groupe t\u00e9moin (ITT)<\/td>\n<\/tr>\n<tr class=\"row-2\">\n\t<td class=\"column-5\">Fonction PULMONAIRE<br \/>\n(%VEMS)<br \/>\nDMCI = 10%\u201315%<\/td><td class=\"column-6\">Capacit\u00e9 d'exercice<br \/>\n(TM6)<br \/>\nDMCI = 26 m<\/td><td class=\"column-7\">QUALIT\u00c9 DE VIE (QRSG)<br \/>\nDMCI = -4 POINTS<\/td>\n<\/tr>\n<tr class=\"row-3\">\n\t<td class=\"column-1\">LIBERATE<a href=\"https:\/\/pulmonx.com\/references\/\" style=\"font-size: 15px;\"><sup>1<\/sup><\/a><\/td><td class=\"column-2\">Randomisation selon un rapport 2:1<br \/>\n<b>H\u00e9t\u00e9rog\u00e8ne uniquement<\/b><br \/>\nMulticentrique<\/td><td class=\"column-3\">n=190<br \/>\n12 Mois<\/td><td class=\"column-4\"><b>84%<\/b><\/td><td class=\"column-5\"><b>18.0%<\/b><br \/>\np<0.001<\/td><td class=\"column-6\"><b>39 m<\/b><br \/>\np=0.002<\/td><td class=\"column-7\"><b>-7.1 points<\/b><br \/>\np=0.004<\/td>\n<\/tr>\n<tr class=\"row-4\">\n\t<td class=\"column-1\">TRANSFORM<a href=\"https:\/\/pulmonx.com\/references\/\" style=\"font-size: 15px;\"><sup>2<\/sup><\/a><\/td><td class=\"column-2\">Randomisation selon un rapport 2:1<br \/>\n<b>H\u00e9t\u00e9rog\u00e8ne uniquement<\/b><br \/>\nMulticentrique<\/td><td class=\"column-3\">n=97<br \/>\n6 Mois<\/td><td class=\"column-4\"><b>90%<\/b><\/td><td class=\"column-5\">29.3%<br \/>\np<0.001<\/td><td class=\"column-6\">79 m<br \/>\np<0.001<\/td><td class=\"column-7\">-6.5 points<br \/>\np=0.031<\/td>\n<\/tr>\n<tr class=\"row-5\">\n\t<td class=\"column-1\">IMPACT<a href=\"https:\/\/pulmonx.com\/references\/\" style=\"font-size: 15px;\"><sup>3<\/sup><\/a><\/td><td class=\"column-2\">Randomisation selon un rapport 1:1<br \/>\n<b>Homog\u00e8ne uniquement<\/b><br \/>\nMulticentrique<\/td><td class=\"column-3\">n=93<br \/>\n6 Mois<\/td><td class=\"column-4\"><b>89%<\/b><\/td><td class=\"column-5\">16.3%<br \/>\np<0.001<\/td><td class=\"column-6\">28 m<br \/>\np=0.016<\/td><td class=\"column-7\">-7.5 points<br \/>\np<0.001<\/td>\n<\/tr>\n<tr class=\"row-6\">\n\t<td class=\"column-1\">STELVIO<a href=\"https:\/\/pulmonx.com\/references\/\" style=\"font-size: 15px;\"><sup>4,5<\/sup><\/a><\/td><td class=\"column-2\">Randomisation selon un rapport 1:1<br \/>\n<b>H\u00e9t\u00e9rog\u00e8ne et Homog\u00e8ne<\/b><br \/>\nMonocentrique<\/td><td class=\"column-3\">n=68<br \/>\n6 Mois<\/td><td class=\"column-4\"><b>88%<\/b><\/td><td class=\"column-5\">17.8%<br \/>\np=0.001<\/td><td class=\"column-6\">74 m<br \/>\np<0.001<\/td><td class=\"column-7\">-14.7 points*<br \/>\np<0.001<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<!-- #tablepress-20 from cache -->\n<h6 class=\"p1\">* Donn\u00e9es en dossier au PMX (non publi\u00e9es)<\/h6>\n<h6 class=\"p1\">**Dossiers clos, toutes les autres valeurs indiqu\u00e9es concernent la population ITT<\/h6>\n<h6 class=\"p1\">T Diff\u00e9rence entre la vanne et les groupes de contr\u00f4le<\/h6>    <\/div>\n<\/div>\n<!-- \/module text --><!-- module image -->\n<div  class=\"module module-image tb_i19w186 image-center   tf_mw hide-desktop hide-tablet_landscape\" data-lazy=\"1\">\n        <div class=\"image-wrap tf_rel tf_mw\">\n            <img decoding=\"async\" width=\"800\" height=\"837\" src=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/07\/Clinical-Table-French.jpg\" class=\"wp-post-image wp-image-76608\" title=\"Clinical-Table-French\" alt=\"Clinical-Table-French\" srcset=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/07\/Clinical-Table-French.jpg 800w, https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/07\/Clinical-Table-French-287x300.jpg 287w, https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/07\/Clinical-Table-French-768x804.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>    \n        <\/div>\n    <!-- \/image-wrap -->\n    \n        <\/div>\n<!-- \/module image --><!-- module text -->\n<div  class=\"module module-text tb_mooi885    hide-desktop hide-tablet_landscape\" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <h6 class=\"p1\">*Dossiers clos, toutes les autres valeurs indiqu\u00e9es concernent la population ITT<\/h6>    <\/div>\n<\/div>\n<!-- \/module text -->        <\/div>\n                  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\"Contr\u00f4le<br>(n=62)\",\r\n\t\t\t\t\t\t\t\"column-2\": \"-4.22\",\r\n\t\t\t\t\t\t\t\"column-3\": \"2.62\",\r\n\t\t\t\t\t\t\t\"Color\": \"#3095b4\",\r\n\t\t\t\t\t\t\t\"STD\": \"26.94\",\r\n\t\t\t\t\t\t\t\"Column Height\": \"-0.8\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"french-homepage-liberate-percent-change-gray\" style=\"width: 100%; height: 400px; background-color: #E6E6E6;\" ><\/div>\r\n\t<\/body>\r\n<\/html><\/p>    <\/div>\n<\/div>\n<!-- \/module text -->        <\/div>\n                    <div  data-lazy=\"1\" class=\"module_column tb-column col4-2 tb_n3q8254 last\">\n                    <!-- module text -->\n<div  class=\"module module-text tb_g8ip671   \" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <h3>Publi\u00e9 dans la revue American Journal of Respiratory and Critical Care Medicine<a style=\"font-size: 15px;\" href=\"\/fr\/la-biographie\/\"><sup>1<\/sup><\/a><\/h3>\n<blockquote>\n<p>\u00ab Les b\u00e9n\u00e9fices sont comparables \u00e0 ceux observ\u00e9s avec la chirurgie de r\u00e9duction du volume pulmonaire (CRVP) mais avec une r\u00e9duction de la morbidit\u00e9 post-proc\u00e9dure. \u00bb<\/p>\n<\/blockquote>\n<ul>\n<li>Essai contr\u00f4l\u00e9 multicentrique, multinational et randomis\u00e9<\/li>\n<li>R\u00e9sultats \u00e0 12 mois<\/li>\n<li>Emphys\u00e8me h\u00e9t\u00e9rog\u00e8ne avec peu, voire aucune ventilation collat\u00e9rale<\/li>\n<li>Avantages cliniquement et statistiquement significatifs par rapport \u00e0 la prise en charge m\u00e9dicale standard actuelle<\/li>\n<li>Am\u00e9lioration des aspects suivants:\n<ul>\n<li>Fonction pulmonaire<\/li>\n<li>Tol\u00e9rance \u00e0 l\u2019effort<\/li>\n<li>Dyspn\u00e9e<\/li>\n<li>Qualit\u00e9 de vie<\/li>\n<\/ul>\n<\/li>\n<\/ul>    <\/div>\n<\/div>\n<!-- \/module text --><!-- module buttons -->\n<div  class=\"module module-buttons tb_0bkp315 buttons-horizontal solid  large squared\" data-lazy=\"1\">\n        <div class=\"module-buttons-item tf_in_flx\">\n                        <a href=\"\/fr\/liberate-etude-clinique\/\" class=\"ui builder_button tf_in_flx tb_default_color\" >\n                                                En savoir plus                                        <\/a>\n                <\/div>\n            <\/div>\n<!-- \/module buttons -->\n        <\/div>\n                        <\/div>\n        <\/div>\n                        <div  data-css_id=\"p4d0618\" data-lazy=\"1\" class=\"module_row themify_builder_row fullwidth tb_p4d0618 tf_w\">\n                        <div class=\"row_inner col_align_top tb_col_count_2 tf_box tf_rel\">\n                        <div  data-lazy=\"1\" class=\"module_column tb-column col4-2 tb_o8cp619 first\">\n                    <!-- module text -->\n<div  class=\"module module-text tb_cnsx620   \" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <h3>Publi\u00e9 dans la revue American Journal of Respiratory and Critical Care Medicine<a style=\"font-size: 15px;\" href=\"\/fr\/la-biographie\/\"><sup>2<\/sup><\/a><\/h3>\n<blockquote>\n<p>\u00ab Les b\u00e9n\u00e9fices sont conformes \u00e0 ceux observ\u00e9s avec la chirurgie de r\u00e9duction du volume pulmonaire (CRVP), et les r\u00e9sultats coh\u00e9rents des essais, la r\u00e9duction potentielle de la morbidit\u00e9 post-proc\u00e9dure et la r\u00e9versibilit\u00e9 de la proc\u00e9dure positionnent le traitement Zephyr comme une option de traitement viable chez ceux qui restent symptomatiques sous traitement m\u00e9dical maximal. \u00bb<\/p>\n<\/blockquote>\n<ul>\n<li>Essai contr\u00f4l\u00e9 multicentrique, multinational et randomis\u00e9<\/li>\n<li>Emphys\u00e8me h\u00e9t\u00e9rog\u00e8ne avec peu, voire aucune ventilation collat\u00e9rale<\/li>\n<li>Avantages cliniquement et statistiquement significatifs par rapport \u00e0 la prise en charge m\u00e9dicale standard actuelle<\/li>\n<li>Am\u00e9lioration des aspects suivants:\n<ul>\n<li>Fonction pulmonaire<\/li>\n<li>Tol\u00e9rance \u00e0 l\u2019effort<\/li>\n<li>Dyspn\u00e9e<\/li>\n<li>Qualit\u00e9 de vie<\/li>\n<\/ul>\n<\/li>\n<\/ul>    <\/div>\n<\/div>\n<!-- \/module text --><!-- module buttons -->\n<div  class=\"module module-buttons tb_vxgn620 buttons-horizontal solid  large squared\" data-lazy=\"1\">\n        <div class=\"module-buttons-item tf_in_flx\">\n                        <a href=\"\/fr\/transform-etude-clinique\/\" class=\"ui builder_button tf_in_flx tb_default_color\" >\n                                                En savoir plus                                        <\/a>\n                <\/div>\n            <\/div>\n<!-- \/module buttons -->\n        <\/div>\n                    <div  data-lazy=\"1\" class=\"module_column tb-column col4-2 tb_bjip620 last\">\n                    <!-- module image -->\n<div  class=\"module module-image tb_cv2v620 image-center   tf_mw\" 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html>\r\n<html>\r\n\t<head>\r\n\t\t<title>Clinical Evidence Page - French: TRANSFORM - FEV1 - Percent Change | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" \/>\r\n\t\t\r\n\t\t<!-- amCharts javascript sources -->\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/amcharts.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/cdn.amcharts.com\/lib\/3\/serial.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/themes\/light.js\"><\/script>\r\n\t\t\r\n\r\n\t\t<!-- amCharts javascript code -->\r\n\t\t<script type=\"text\/javascript\">\r\n\t\t\tAmCharts.makeChart(\"french-clinical-evidence-page-transform\",\r\n\t\t\t\t{\r\n\t\t\t\t\t\"hideCredits\": \"true\",\r\n              \t\t\"type\": \"serial\",\r\n\t\t\t\t\t\"categoryField\": \"category\",\r\n\t\t\t\t\t\"autoMarginOffset\": 0,\r\n\t\t\t\t\t\"autoMargins\": 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background-color: #E6E6E6;\" ><\/div>\r\n\t<\/body>\r\n<\/html><\/p>    <\/div>\n<\/div>\n<!-- \/module text -->        <\/div>\n                    <div  data-lazy=\"1\" class=\"module_column tb-column col4-2 tb_fmas454 last\">\n                    <!-- module text -->\n<div  class=\"module module-text tb_kxrs455   \" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <h3>Publi\u00e9 dans la revue American Journal of Respiratory and Critical Care Medicine<a style=\"font-size: 15px;\" href=\"\/fr\/la-biographie\/\"><sup>3<\/sup><\/a><\/h3>\n<blockquote>\n<p>Le traitement par la VEB chez des patients s\u00e9lectionn\u00e9s atteints d\u2019un emphys\u00e8me homog\u00e8ne et ne pr\u00e9sentant pas de ventilation collat\u00e9rale a donn\u00e9 lieu \u00e0 des b\u00e9n\u00e9fices cliniquement significatifs concernant l\u2019am\u00e9lioration de la fonction pulmonaire, de la tol\u00e9rance \u00e0 l\u2019effort et de la qualit\u00e9 de vie. \u00ab Compte tenu des options th\u00e9rapeutiques tr\u00e8s limit\u00e9es dont on dispose pour cette population de patients, le traitement par la VEB doit \u00eatre envisag\u00e9 chez ces personnes. \u00bb<\/p>\n<\/blockquote>\n<ul>\n<li>Essai prospectif contr\u00f4l\u00e9 et randomis\u00e9<\/li>\n<li>Emphys\u00e8me homog\u00e8ne avec peu, voire aucune ventilation collat\u00e9rale<\/li>\n<li>Avantages cliniquement significatifs dans:\n<ul>\n<li>Fonction pulmonaire<\/li>\n<li>Tol\u00e9rance \u00e0 l\u2019effort<\/li>\n<li>Qualit\u00e9 de vie<\/li>\n<\/ul>\n<\/li>\n<\/ul>    <\/div>\n<\/div>\n<!-- \/module text -->        <div  data-lazy=\"1\" class=\"module_subrow themify_builder_sub_row tf_w col_align_top tb_col_count_2 tb_grxg107\">\n                <div  data-lazy=\"1\" class=\"module_column sub_column tb_glod109 first\">\n                    <!-- module buttons -->\n<div  class=\"module module-buttons tb_t4gf455 buttons-horizontal solid  large squared\" data-lazy=\"1\">\n        <div class=\"module-buttons-item tf_in_flx\">\n                        <a href=\"https:\/\/vimeo.com\/367117938\" class=\"ui builder_button tf_in_flx tb_default_color\" target=\"_blank\" rel=\"noopener\">\n                                                Visionner le webinaire                                        <\/a>\n                <\/div>\n            <\/div>\n<!-- \/module buttons -->\n        <\/div>\n                    <div  data-lazy=\"1\" class=\"module_column sub_column tb_fa8i109 last\">\n                    <!-- module buttons -->\n<div  class=\"module module-buttons tb_q29u115 buttons-horizontal solid  large squared\" data-lazy=\"1\">\n        <div class=\"module-buttons-item tf_in_flx\">\n                        <a href=\"\/fr\/impact-etude-clinique\/\" class=\"ui builder_button tf_in_flx tb_default_color\" >\n                                                En savoir plus                                        <\/a>\n                <\/div>\n            <\/div>\n<!-- \/module buttons -->\n        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clinique mesurable, avec une am\u00e9lioration significative de la fonction respiratoire, de la capacit\u00e9 \u00e0 faire de l\u2019exercice et de la qualit\u00e9 de vie par rapport \u00e0 un traitement m\u00e9dical st standard. \u00bb<\/p>\n<\/blockquote>\n<ul>\n<li>Essai prospectif contr\u00f4l\u00e9 et randomis\u00e9<\/li>\n<li>Premi\u00e8re \u00e9tude randomis\u00e9e \u00e0 utiliser Chartis<sup>\u00ae<\/sup> pour pr\u00e9s\u00e9lectionner les candidats<\/li>\n<li>Emphys\u00e8me avec peu, voire aucune ventilation collat\u00e9rale<\/li>\n<li>Am\u00e9liorations statistiquement et cliniquement plus importantes comparativement au groupe t\u00e9moin en ce qui concerne les \u00e9l\u00e9ments suivants:\n<ul>\n<li>Fonction pulmonaire (VEMS<sub>1<\/sub> et CVF)<\/li>\n<li>Capacit\u00e9 \u00e0 faire de l\u2019exercice<\/li>\n<li>Qualit\u00e9 de vie<\/li>\n<\/ul>\n<\/li>\n<li>Suivi d&rsquo;un an publi\u00e9 dans la revue American Journal of Respiratory and Critical Care Medicine<a 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\"Contr\u00f4le<br>(n=34)\",\r\n\t\t\t\t\t\t\t\"column-2\": \"-0.4\",\r\n\t\t\t\t\t\t\t\"column-3\": \"6.6\",\r\n\t\t\t\t\t\t\t\"Color\": \"#3095b4\",\r\n\t\t\t\t\t\t\t\"Column Height\": \"3.1\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"french-clinical-evidence-page-stelvio\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html><\/p>    <\/div>\n<\/div>\n<!-- \/module text -->        <\/div>\n                        <\/div>\n        <\/div>\n                        <div  data-css_id=\"f75g984\" data-lazy=\"1\" class=\"module_row themify_builder_row fullwidth tb_f75g984 tf_w\">\n            <span class=\"tb_row_frame_wrap tf_overflow tf_abs\" data-lazy=\"1\"><span class=\"tb_row_frame tb_row_frame_top  tf_abs tf_hide tf_overflow tf_w\"><\/span><\/span>            <div class=\"row_inner col_align_top tb_col_count_3 tf_box tf_rel\">\n                        <div  data-lazy=\"1\" class=\"module_column tb-column col4-1 tb_fell986 first\">\n                    <!-- module divider -->\n<div  class=\"module tf_mw module-divider tb_jlv3987 solid   \" style=\"border-width: 0px;border-color: #ffffff;margin-top: 30px;margin-bottom: 8px;\" data-lazy=\"1\">\n    <\/div>\n<!-- \/module divider -->\n        <\/div>\n                    <div  data-lazy=\"1\" class=\"module_column tb-column col4-2 tb_nubv417\">\n                    <!-- module text -->\n<div  class=\"module module-text tb_y1ww987   \" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <h2 style=\"text-align: center;\"><strong>Les documents d&rsquo;orientation internationaux incluent le traitement par valve endobronchique comme option pour les patients souffrant d&#8217;emphys\u00e8me<\/strong><\/h2>\n<p style=\"text-align: center;\">Plusieurs organisations ind\u00e9pendantes ont conclu que moyennant une s\u00e9lection judicieuse des patients, la proc\u00e9dure d&rsquo;implantation des valves Zephyr devrait \u00eatre envisag\u00e9e dans le traitement de l&#8217;emphys\u00e8me s\u00e9v\u00e8re.<\/p>    <\/div>\n<\/div>\n<!-- \/module text -->        <div  data-lazy=\"1\" class=\"module_subrow themify_builder_sub_row tf_w col_align_top tb_col_count_2 tb_popy445\">\n                <div  data-lazy=\"1\" class=\"module_column sub_column tb_ampw447 first\">\n                    <!-- module text -->\n<div  class=\"module module-text tb_m2dy511   \" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <p>La qualit\u00e9 des preuves pour le traitement par valves endobronchiques a \u00e9t\u00e9 not\u00e9e \u00ab A \u00bb par l&rsquo;initiative GOLD (Global Initiative for Chronic Obstructive Lung Disease).<a href=\"\/fr\/la-biographie\/\"><sup>10<\/sup><\/a><\/p>    <\/div>\n<\/div>\n<!-- \/module text -->        <\/div>\n                    <div  data-lazy=\"1\" class=\"module_column sub_column tb_3io2448 last\">\n                    <!-- module text -->\n<div  class=\"module module-text tb_fsh2597   \" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <p>Le National Institute for Care and Excellence (NICE) du Royaume-Uni a inclus ce traitement dans les mesures standard pour la BPCO et a recommand\u00e9 que tous les patients admissibles soient \u00e9valu\u00e9s afin de d\u00e9terminer leur \u00e9ligibilit\u00e9.<a href=\"\/fr\/la-biographie\/\"><sup>11,34<\/sup><\/a><\/p>    <\/div>\n<\/div>\n<!-- \/module text -->        <\/div>\n                    <\/div>\n                <div  data-lazy=\"1\" class=\"module_subrow themify_builder_sub_row tf_w col_align_top tb_col_count_2 tb_5ezp562\">\n                <div  data-lazy=\"1\" class=\"module_column sub_column col4-2 tb_6pmq563 first\">\n                    <!-- module image -->\n<div  class=\"module module-image tb_ppn5483 image-center   tf_mw\" data-lazy=\"1\">\n        <div class=\"image-wrap tf_rel tf_mw\">\n            <a href=\"https:\/\/goldcopd.org\/gold-reports\/\" rel=\"noopener\" target=\"_blank\">\n                   <img decoding=\"async\" src=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/GOLD-Guidelines-Zephyr-Valve-350x168.png\" width=\"350\" height=\"168\" class=\"wp-post-image wp-image-75403\" title=\"GOLD-Guidelines-Zephyr-Valve\" alt=\"GOLD-Guidelines-Zephyr-Valve\" srcset=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/GOLD-Guidelines-Zephyr-Valve-350x168.png 350w, https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/GOLD-Guidelines-Zephyr-Valve-300x145.png 300w, https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/GOLD-Guidelines-Zephyr-Valve-768x371.png 768w, https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/GOLD-Guidelines-Zephyr-Valve.png 800w\" sizes=\"(max-width: 350px) 100vw, 350px\" \/>        <\/a>\n    \n        <\/div>\n    <!-- \/image-wrap -->\n    \n        <\/div>\n<!-- \/module image -->        <\/div>\n                    <div  data-lazy=\"1\" class=\"module_column sub_column col4-2 tb_uds4563 last\">\n                    <!-- module image -->\n<div  class=\"module module-image tb_x8n6579 image-center   tf_mw\" data-lazy=\"1\">\n        <div class=\"image-wrap tf_rel tf_mw\">\n            <a href=\"https:\/\/www.nice.org.uk\/guidance\/ipg600\" rel=\"noopener\" target=\"_blank\">\n                   <img decoding=\"async\" src=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/NICE-Guidelines-Zephyr-Valve-350x168.png\" width=\"350\" height=\"168\" class=\"wp-post-image wp-image-75401\" title=\"NICE-Guidelines-Zephyr-Valve\" alt=\"NICE-Guidelines-Zephyr-Valve\" srcset=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/NICE-Guidelines-Zephyr-Valve-350x168.png 350w, https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/NICE-Guidelines-Zephyr-Valve-300x145.png 300w, https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/NICE-Guidelines-Zephyr-Valve-768x371.png 768w, https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/NICE-Guidelines-Zephyr-Valve.png 800w\" sizes=\"(max-width: 350px) 100vw, 350px\" \/>        <\/a>\n    \n        <\/div>\n    <!-- \/image-wrap -->\n    \n        <\/div>\n<!-- \/module image -->        <\/div>\n                    <\/div>\n                <div  data-lazy=\"1\" class=\"module_subrow themify_builder_sub_row tf_w col_align_top tb_col_count_2 tb_fk2u873\">\n                <div  data-lazy=\"1\" class=\"module_column sub_column col4-2 tb_8lpz874 first\">\n                    <!-- module image -->\n<div  class=\"module module-image tb_77oz13 image-center   tf_mw\" data-lazy=\"1\">\n        <div class=\"image-wrap tf_rel tf_mw\">\n            <a href=\"https:\/\/www.awmf.org\/leitlinien\/detail\/ll\/020-006.html\" rel=\"noopener\" target=\"_blank\">\n                   <img decoding=\"async\" src=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/DGP-Guidelines-Zephyr-Valve-350x168.png\" width=\"350\" height=\"168\" class=\"wp-post-image wp-image-75404\" title=\"DGP-Guidelines-Zephyr-Valve\" alt=\"DGP-Guidelines-Zephyr-Valve\" srcset=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/DGP-Guidelines-Zephyr-Valve-350x168.png 350w, https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/DGP-Guidelines-Zephyr-Valve-300x145.png 300w, https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/DGP-Guidelines-Zephyr-Valve-768x371.png 768w, https:\/\/pulmonx.com\/wp-content\/uploads\/2019\/09\/DGP-Guidelines-Zephyr-Valve.png 800w\" sizes=\"(max-width: 350px) 100vw, 350px\" \/>        <\/a>\n    \n        <\/div>\n    <!-- \/image-wrap -->\n    \n        <\/div>\n<!-- \/module image -->        <\/div>\n                    <div  data-lazy=\"1\" class=\"module_column sub_column col4-2 tb_99a8875 last\">\n                    <!-- module image -->\n<div  class=\"module module-image tb_a0d3875 image-center   tf_mw\" data-lazy=\"1\">\n        <div class=\"image-wrap tf_rel tf_mw\">\n            <a href=\"https:\/\/english.zorginstituutnederland.nl\/\" rel=\"noopener\" target=\"_blank\">\n                   <img decoding=\"async\" src=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/05\/PMX-Corporate-Website-Assets_ForTranslation-French-ZIN-350x175.png\" width=\"350\" height=\"175\" class=\"wp-post-image wp-image-75882\" title=\"PMX-Corporate-Website-Assets_ForTranslation-French-ZIN\" alt=\"PMX-Corporate-Website-Assets_ForTranslation-French-ZIN\" srcset=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/05\/PMX-Corporate-Website-Assets_ForTranslation-French-ZIN-350x175.png 350w, https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/05\/PMX-Corporate-Website-Assets_ForTranslation-French-ZIN-300x150.png 300w, https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/05\/PMX-Corporate-Website-Assets_ForTranslation-French-ZIN-768x384.png 768w, https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/05\/PMX-Corporate-Website-Assets_ForTranslation-French-ZIN.png 800w\" sizes=\"(max-width: 350px) 100vw, 350px\" \/>        <\/a>\n    \n        <\/div>\n    <!-- \/image-wrap -->\n    \n        <\/div>\n<!-- \/module image -->        <\/div>\n                    <\/div>\n                <\/div>\n                    <div  data-lazy=\"1\" class=\"module_column tb-column col4-1 tb_jz4c419 last\">\n                            <\/div>\n                        <\/div>\n        <\/div>\n                        <div  data-css_id=\"2sl4723\" data-lazy=\"1\" class=\"module_row themify_builder_row fullwidth tb_2sl4723 tf_w\">\n                        <div class=\"row_inner col_align_top tb_col_count_2 tf_box tf_rel\">\n                        <div  data-lazy=\"1\" class=\"module_column tb-column col4-3 tb_t9vz725 first\">\n                    <!-- module text -->\n<div  class=\"module module-text tb_7vr3791   \" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <h2 style=\"text-align: center;\">Pr\u00e9f\u00e9rence de traitement des patients<\/h2>    <\/div>\n<\/div>\n<!-- \/module text -->        <div  data-lazy=\"1\" class=\"module_subrow themify_builder_sub_row tf_w col_align_top tb_col_count_2 tb_q57d322\">\n                <div  data-lazy=\"1\" class=\"module_column sub_column col4-2 tb_z49l323 first\">\n                    <!-- module image -->\n<div  class=\"module module-image tb_18eb867 image-top   tf_mw\" data-lazy=\"1\">\n        <div class=\"image-wrap tf_rel tf_mw\">\n            <a href=\"\/references\">\n                   <img decoding=\"async\" width=\"800\" height=\"800\" src=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/05\/PMX-Corporate-Website-Assets_ForTranslation-French-3in4.png\" class=\"wp-post-image wp-image-75807\" title=\"PMX-Corporate-Website-Assets_ForTranslation-French-3in4\" alt=\"PMX-Corporate-Website-Assets_ForTranslation-French-3in4\" srcset=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/05\/PMX-Corporate-Website-Assets_ForTranslation-French-3in4.png 800w, https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/05\/PMX-Corporate-Website-Assets_ForTranslation-French-3in4-300x300.png 300w, https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/05\/PMX-Corporate-Website-Assets_ForTranslation-French-3in4-150x150.png 150w, https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/05\/PMX-Corporate-Website-Assets_ForTranslation-French-3in4-768x768.png 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>        <\/a>\n    \n        <\/div>\n    <!-- \/image-wrap -->\n    \n        <\/div>\n<!-- \/module image -->        <\/div>\n                    <div  data-lazy=\"1\" class=\"module_column sub_column col4-2 tb_5f58323 last\">\n                    <!-- module text -->\n<div  class=\"module module-text tb_7bgq159   \" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <p>Une enqu\u00eate d\u00e9taill\u00e9e men\u00e9e aupr\u00e8s de 294 patients atteints d\u2019emphys\u00e8me s\u00e9v\u00e8re \u00e9valuait la mani\u00e8re dont ils mettaient en balance les risques et les b\u00e9n\u00e9fices potentiels. L\u2019\u00e9tude a conclu que les patients atteints d\u2019emphys\u00e8me s\u00e9v\u00e8re appr\u00e9cient un traitement interventionnel avec des avantages sup\u00e9rieurs \u00e0 leur prise en charge m\u00e9dicale actuelle, malgr\u00e9 les risques associ\u00e9s \u00e0 ces traitements.<a style=\"font-size: 15px;\" href=\"\/fr\/la-biographie\/\"><sup>8<\/sup><\/a><\/p>    <\/div>\n<\/div>\n<!-- \/module text --><!-- module buttons -->\n<div  class=\"module module-buttons tb_o011353 buttons-horizontal solid  large squared\" data-lazy=\"1\">\n        <div class=\"module-buttons-item tf_in_flx\">\n                        <a href=\"\/fr\/histoires-de-patients\/\" class=\"ui builder_button tf_in_flx tb_default_color\" >\n                                                En savoir plus                                        <\/a>\n                <\/div>\n            <\/div>\n<!-- \/module buttons -->\n        <\/div>\n                    <\/div>\n                <\/div>\n                    <div  data-lazy=\"1\" class=\"module_column tb-column col4-1 tb_tjez666 last\">\n                            <\/div>\n                        <\/div>\n        <\/div>\n                        <div  data-lazy=\"1\" class=\"module_row themify_builder_row tb_s9q0400 tf_w\">\n                        <div class=\"row_inner col_align_top tb_col_count_1 tf_box tf_rel\">\n                        <div  data-lazy=\"1\" class=\"module_column tb-column col-full tb_78j0402 first\">\n                    <!-- module text -->\n<div  class=\"module module-text tb_heit532   \" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <h2 style=\"text-align: center;\">Besoin d&rsquo;informations compl\u00e9mentaires ?<\/h2>    <\/div>\n<\/div>\n<!-- \/module text -->        <div  data-lazy=\"1\" class=\"module_subrow themify_builder_sub_row tf_w col_align_top tb_col_count_4 tb_g6on45\">\n                <div  data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_0o4b46 first\">\n                            <\/div>\n                    <div  data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_z1gj46\">\n                    <!-- module buttons -->\n<div  class=\"module module-buttons tb_vrsg75 buttons-horizontal solid  large squared\" data-lazy=\"1\">\n        <div class=\"module-buttons-item tf_in_flx\">\n                        <a href=\"\/fr\/la-biographie\/\" class=\"ui builder_button tf_in_flx tb_default_color\" >\n                                                Afficher la biographie compl\u00e8te                                        <\/a>\n                <\/div>\n            <\/div>\n<!-- \/module buttons -->\n        <\/div>\n                    <div  data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_st2b47\">\n                    <!-- module buttons -->\n<div  class=\"module module-buttons tb_9558995 buttons-horizontal solid  large squared\" data-lazy=\"1\">\n        <div class=\"module-buttons-item tf_in_flx\">\n                        <a href=\"\/fr\/telecharger-les-etudes-cliniques\/\" class=\"ui builder_button tf_in_flx tb_default_color\" >\n                                                T\u00e9l\u00e9charger les \u00e9tudes cliniques                                        <\/a>\n                <\/div>\n            <\/div>\n<!-- \/module buttons -->\n        <\/div>\n                    <div  data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_5qfi47 last\">\n                            <\/div>\n                    <\/div>\n                <div  data-lazy=\"1\" class=\"module_subrow themify_builder_sub_row tf_w col_align_top tb_col_count_1 tb_mld6805\">\n                <div  data-lazy=\"1\" class=\"module_column sub_column col-full tb_153e807 first\">\n                    <!-- module text -->\n<div  class=\"module module-text tb_yk19651   \" data-lazy=\"1\">\n        <div  class=\"tb_text_wrap\">\n        <h6>*En intention de traiter<\/h6>    <\/div>\n<\/div>\n<!-- \/module text -->        <\/div>\n                    <\/div>\n                <\/div>\n                        <\/div>\n        <\/div>\n        <\/div>\n<!--\/themify_builder_content-->","protected":false},"excerpt":{"rendered":"<p>&gt;100 articles scientifiques publi\u00e9s Les r\u00e9sultats de plusieurs essais cliniques randomis\u00e9s portant sur la valve Zephyr\u00ae ont d\u00e9montr\u00e9 des avantages cliniquement significatifs en termes de fonction pulmonaire, de capacit\u00e9 \u00e0 faire de l\u2019exercice et de qualit\u00e9 de vie (QV)1-5 4 ECR publi\u00e9s sur l&rsquo;utilisation de la valve Zephyr et de Chartis\u00ae pour pr\u00e9s\u00e9lectionner les patients1-5 [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-75417","page","type-page","status-publish","hentry","has-post-title","has-post-date","has-post-category","has-post-tag","has-post-comment","has-post-author",""],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Preuves cliniques - Pulmonx<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pulmonx.com\/fr\/preuves-cliniques\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Preuves cliniques - Pulmonx\" \/>\n<meta property=\"og:description\" content=\"&gt;100 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