{"id":74898,"date":"2020-04-15T10:52:08","date_gmt":"2020-04-15T15:52:08","guid":{"rendered":"https:\/\/pulmonx.com\/stelvio-estudio-clinico\/"},"modified":"2021-05-03T14:43:44","modified_gmt":"2021-05-03T19:43:44","slug":"stelvio-estudio-clinico","status":"publish","type":"post","link":"https:\/\/pulmonx.com\/es\/stelvio-estudio-clinico\/","title":{"rendered":"STELVIO Estudio cl\u00ednico"},"content":{"rendered":"\n
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\n \"Stelvio-Estudio-Clinico\" \n <\/div>\n \n \n <\/div>\n\n
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El tratamiento con v\u00e1lvulas endobronquiales en pacientes con enfisema y una ausencia probada de ventilaci\u00f3n colateral proporcionaron un beneficio cuantificable cl\u00ednicamente significativo, con una funci\u00f3n pulmonar considerablemente mejor, mayor capacidad de ejercicio y una calidad de vida mejorada en comparaci\u00f3n con el tratamiento de referencia.4<\/sup><\/p>\n

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Publicado en The New England Journal of Medicine4<\/sup><\/a><\/h1>\n

El primer ensayo controlado aleatorizado en el que se utiliz\u00f3 Chartis\u00ae<\/sup> para seleccionar a candidatos para someterse a un tratamiento con v\u00e1lvulas endobronquiales Zephyr.<\/p>\n

M\u00e9todos y criterios de valoraci\u00f3n<\/b><\/h3>\n
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  • 68 pacientes confirmados como negativos a la ventilaci\u00f3n colateral (VC) con el sistema Chartis y que probablemente responder\u00edan al tratamiento con v\u00e1lvulas Zephyr\u00ae<\/sup>, que se aleatorizaron en una proporci\u00f3n 1:1 para el tratamiento con v\u00e1lvulas Zephyr o el tratamiento est\u00e1ndar.<\/li>\n
  • Las variables principales evaluadas fueron las diferencias observadas entre los grupos con relaci\u00f3n al VEF1<\/sub>, la CVF y una prueba de marcha de 6 minutos (DR6) teniendo en cuenta los valores iniciales y los valores a los 6 meses.<\/li>\n<\/ul> <\/div>\n<\/div>\n <\/div>\n <\/div>\n <\/div>\n
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    Dise\u00f1o del ensayo<\/h2> <\/div>\n<\/div>\n\n
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    \n \"STELVIO-Study-Design-Spanish-1\" \n <\/div>\n \n \n <\/div>\n\n
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    *El ensayo STELVIO fue un ensayo iniciado y realizado por un m\u00e9dico independiente. Pulmonx no particip\u00f3 en ninguna parte del ensayo.<\/p>\n <\/div>\n<\/div>\n\n

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    Resultados<\/h2> <\/div>\n<\/div>\n <\/div>\n <\/div>\n
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    Resultados principales en la poblaci\u00f3n por intenci\u00f3n de tratar<\/h4>\n

    Cambio medio con respecto al valor inicial transcurridos 6 meses<\/p> <\/div>\n<\/div>\n <\/div>\n

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    VEF1<\/sub><\/h5>\n

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Cambio medio a partir del valor inicial.<\/p> <\/div>\n<\/div>\n<!-- \/module text --><!-- module text -->\n<div class=\"module module-text tb_f26i346 hide-tablet hide-mobile\" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n \n<table id=\"tablepress-15\" class=\"tablepress tablepress-id-15 stelvio\">\n<tbody class=\"row-striping\">\n<tr class=\"row-1\">\n\t<td class=\"column-1\"><\/td><td class=\"column-2\">Enfisema homog\u00e9neo (n=29)<\/td><td class=\"column-3\">Enfisema heterog\u00e9neo (n=22)<\/td>\n<\/tr>\n<tr class=\"row-2\">\n\t<td class=\"column-1\">VEF<sub>1<\/sub> (%)<\/td><td class=\"column-2\">+20,1<\/td><td class=\"column-3\">+32,6<\/td>\n<\/tr>\n<tr class=\"row-3\">\n\t<td class=\"column-1\">VR (%)<\/td><td class=\"column-2\">-16,3<\/td><td class=\"column-3\">-16,6<\/td>\n<\/tr>\n<tr class=\"row-4\">\n\t<td class=\"column-1\">PM6M (metros)<\/td><td class=\"column-2\">+69<\/td><td class=\"column-3\">+72<\/td>\n<\/tr>\n<tr class=\"row-5\">\n\t<td class=\"column-1\">CRSG (puntos)<\/td><td class=\"column-2\">-13<\/td><td class=\"column-3\">-19<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<!-- #tablepress-15 from cache --> <\/div>\n<\/div>\n<!-- \/module text --><!-- module image -->\n<div class=\"module module-image tb_9gtj639 image-center tf_mw hide-desktop hide-tablet_landscape\" data-lazy=\"1\">\n <div class=\"image-wrap tf_rel tf_mw\">\n <img decoding=\"async\" width=\"845\" height=\"261\" src=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/04\/Stelvio-Table-2-Espanol.png\" class=\"wp-post-image wp-image-75370\" title=\"Stelvio-Table-2-Espanol\" alt=\"Stelvio-Table-2-Espanol\" srcset=\"https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/04\/Stelvio-Table-2-Espanol.png 845w, https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/04\/Stelvio-Table-2-Espanol-300x93.png 300w, https:\/\/pulmonx.com\/wp-content\/uploads\/2020\/04\/Stelvio-Table-2-Espanol-768x237.png 768w\" sizes=\"(max-width: 845px) 100vw, 845px\" \/> \n <\/div>\n <!-- \/image-wrap -->\n \n <\/div>\n<!-- \/module image --><!-- module text -->\n<div class=\"module module-text tb_xhsd472 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h3 class=\"p1\">Tasas de respuesta significativamente superiores para pacientes tratados con v\u00e1lvulas Zephyr en comparaci\u00f3n con el tratamiento de referencia<\/h3>\n<p class=\"p2\">Resultados de MCID de pacientes que respondieron y que completaron el ensayo<\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <\/div>\n <div data-lazy=\"1\" class=\"module_subrow themify_builder_sub_row tf_w col_align_top tb_col_count_4 tb_ojvn222\">\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_akwx224 first\">\n <!-- module text -->\n<div class=\"module module-text tb_l2lp137 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <p class=\"p1\">Cambio en el VEF<span class=\"s1\"><sub>1<\/sub><\/span> <\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 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id=\"spanish-stelvio-fev1-control-group\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html> <\/div>\n<\/div>\n<!-- \/module plain text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_pdv8225\">\n <!-- module text -->\n<div class=\"module module-text tb_uj4n492 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h5 style=\"text-align: center;\">Grupo de la v\u00e1lvula Zephyr<br>n=25<\/h5> <\/div>\n<\/div>\n<!-- \/module text --><!-- module plain text -->\n<div class=\"module module-plain-text tb_nh4p308 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>STELVIO Study Page - Spanish: STELVIO - FEV1 - Zephyr Valve | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" \/>\r\n\t\t\r\n\t\t<!-- amCharts javascript sources -->\r\n\t\t<script type=\"text\/javascript\" 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\"#4F2D7F\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"spanish-stelvio-fev1-zephyr-valve\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html> <\/div>\n<\/div>\n<!-- \/module plain text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_iloh334 last\">\n <!-- module text -->\n<div class=\"module module-text tb_as6s700 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h5 style=\"text-align: center;\">Grupo cruzado con grupo de la v\u00e1lvula Zephyr<br>n=26<\/h5> <\/div>\n<\/div>\n<!-- \/module text --><!-- module plain text -->\n<div class=\"module module-plain-text tb_5293214 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>STELVIO Study Page - Spanish: STELVIO - FEV1 - Crossover | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live 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\"\",\r\n\t\t\t\t\t\t\t\"column-1\": \"60.67\",\r\n\t\t\t\t\t\t\t\"Color\": \"#FF5C39\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"\",\r\n\t\t\t\t\t\t\t\"column-1\": \"95.24\",\r\n\t\t\t\t\t\t\t\"Color\": \"#FF5C39\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"spanish-stelvio-fev1-crossover\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html> <\/div>\n<\/div>\n<!-- \/module plain text --> <\/div>\n <\/div>\n <div data-lazy=\"1\" class=\"module_subrow themify_builder_sub_row tf_w col_align_top tb_col_count_4 tb_3uxs997\">\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_uy3s998 first\">\n <!-- module text -->\n<div class=\"module module-text tb_7cpn999 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <p class=\"p1\">Cambio en la DR6<\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_x11u999\">\n <!-- module text -->\n<div class=\"module module-text tb_2si50 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h5 style=\"text-align: center;\">Grupo de control<br>n=33<\/h5> <\/div>\n<\/div>\n<!-- \/module text --><!-- module plain text -->\n<div class=\"module module-plain-text tb_m63841 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>STELVIO Study Page - Spanish: STELVIO - 6MWD - Control Group | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" \/>\r\n\t\t\r\n\t\t<!-- amCharts javascript sources -->\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/amcharts.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/cdn.amcharts.com\/lib\/3\/serial.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/themes\/light.js\"><\/script>\r\n\t\t\r\n\r\n\t\t<!-- amCharts javascript code -->\r\n\t\t<script type=\"text\/javascript\">\r\n\t\t\tAmCharts.makeChart(\"spanish-stelvio-6mwd-control-group\",\r\n\t\t\t\t{\r\n \t\t\"hideCredits\": \"true\",\r\n\t\t\t\t\t\"type\": \"serial\",\r\n\t\t\t\t\t\"categoryField\": \"category\",\r\n\t\t\t\t\t\"autoMarginOffset\": 0,\r\n\t\t\t\t\t\"autoMargins\": false,\r\n\t\t\t\t\t\"marginBottom\": 60,\r\n\t\t\t\t\t\"marginLeft\": 68,\r\n\t\t\t\t\t\"marginRight\": 95,\r\n\t\t\t\t\t\"marginTop\": 55,\r\n\t\t\t\t\t\"plotAreaFillColors\": \"\",\r\n\t\t\t\t\t\"startDuration\": 2,\r\n\t\t\t\t\t\"startEffect\": \"easeOutSine\",\r\n\t\t\t\t\t\"accessibleTitle\": \"cambioenladr6grupodecontroln33\",\r\n\t\t\t\t\t\"backgroundAlpha\": 0.8,\r\n\t\t\t\t\t\"borderColor\": \"\",\r\n\t\t\t\t\t\"decimalSeparator\": \",\",\r\n\t\t\t\t\t\"fontFamily\": \"Arial\",\r\n\t\t\t\t\t\"fontSize\": 14,\r\n\t\t\t\t\t\"pathToImages\": 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\"#3095B4\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"spanish-stelvio-6mwd-control-group\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html> <\/div>\n<\/div>\n<!-- \/module plain text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_xfsv0\">\n <!-- module text -->\n<div class=\"module module-text tb_kedb0 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h5 style=\"text-align: center;\">Grupo de la v\u00e1lvula Zephyr<br>n=25<\/h5> <\/div>\n<\/div>\n<!-- \/module text --><!-- module plain text -->\n<div class=\"module module-plain-text tb_s7o4650 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>STELVIO Study Page - Spanish: STELVIO - 6MWD - Zephyr Valve | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" 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<\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_5aw80 last\">\n <!-- module text -->\n<div class=\"module module-text tb_l00m1 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h5 style=\"text-align: center;\">Grupo cruzado con grupo de la v\u00e1lvula Zephyr<br>n=26<\/h5> <\/div>\n<\/div>\n<!-- \/module text --><!-- module plain text -->\n<div class=\"module module-plain-text tb_aq8q777 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>STELVIO Study Page - Spanish: STELVIO - 6MWD - Crossover | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" \/>\r\n\t\t\r\n\t\t<!-- amCharts javascript sources -->\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/amcharts.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/cdn.amcharts.com\/lib\/3\/serial.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/themes\/light.js\"><\/script>\r\n\t\t\r\n\r\n\t\t<!-- amCharts javascript code -->\r\n\t\t<script type=\"text\/javascript\">\r\n\t\t\tAmCharts.makeChart(\"spanish-stelvio-6mwd-crossover\",\r\n\t\t\t\t{\r\n \t\t\"hideCredits\": \"true\",\r\n\t\t\t\t\t\"type\": \"serial\",\r\n\t\t\t\t\t\"categoryField\": \"category\",\r\n\t\t\t\t\t\"autoMarginOffset\": 0,\r\n\t\t\t\t\t\"autoMargins\": false,\r\n\t\t\t\t\t\"marginBottom\": 60,\r\n\t\t\t\t\t\"marginLeft\": 68,\r\n\t\t\t\t\t\"marginRight\": 95,\r\n\t\t\t\t\t\"marginTop\": 55,\r\n\t\t\t\t\t\"plotAreaFillColors\": \"\",\r\n\t\t\t\t\t\"startDuration\": 2,\r\n\t\t\t\t\t\"startEffect\": \"easeOutSine\",\r\n\t\t\t\t\t\"accessibleTitle\": \"stelviocambioenladr6grupocruzadocongrupodelavalvulazephyrn26\",\r\n\t\t\t\t\t\"backgroundAlpha\": 0.8,\r\n\t\t\t\t\t\"borderColor\": \"\",\r\n\t\t\t\t\t\"decimalSeparator\": \",\",\r\n\t\t\t\t\t\"fontFamily\": \"Arial\",\r\n\t\t\t\t\t\"fontSize\": 14,\r\n\t\t\t\t\t\"pathToImages\": \"http:\/\/cdn.amcharts.com\/lib\/3\/images\/\",\r\n\t\t\t\t\t\"theme\": \"light\",\r\n\t\t\t\t\t\"categoryAxis\": {\r\n\t\t\t\t\t\t\"classNameField\": \"\",\r\n\t\t\t\t\t\t\"gridPosition\": \"start\",\r\n\t\t\t\t\t\t\"axisThickness\": 0,\r\n\t\t\t\t\t\t\"boldLabels\": true,\r\n\t\t\t\t\t\t\"centerLabels\": true,\r\n\t\t\t\t\t\t\"fontSize\": 14,\r\n\t\t\t\t\t\t\"gridColor\": \"#FFFFFF\",\r\n\t\t\t\t\t\t\"tickLength\": 0,\r\n\t\t\t\t\t\t\"title\": \"\"\r\n\t\t\t\t\t},\r\n\t\t\t\t\t\"trendLines\": [],\r\n\t\t\t\t\t\"graphs\": [\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"accessibleLabel\": \"STELVIO - Cambio en la DR6 - Grupo cruzado con grupo de la v\u00e1lvula Zephyr n =26\",\r\n\t\t\t\t\t\t\t\"balloonText\": \"\",\r\n\t\t\t\t\t\t\t\"colorField\": \"Color\",\r\n\t\t\t\t\t\t\t\"customMarker\": \"\",\r\n\t\t\t\t\t\t\t\"fillAlphas\": 1,\r\n\t\t\t\t\t\t\t\"id\": \"AmGraph-1\",\r\n\t\t\t\t\t\t\t\"labelText\": \"\",\r\n\t\t\t\t\t\t\t\"legendColor\": \"#FF5C39\",\r\n\t\t\t\t\t\t\t\"legendPeriodValueText\": \"\",\r\n\t\t\t\t\t\t\t\"lineColor\": \"\",\r\n\t\t\t\t\t\t\t\"lineThickness\": 0,\r\n\t\t\t\t\t\t\t\"negativeFillAlphas\": 0,\r\n\t\t\t\t\t\t\t\"negativeFillColors\": \"\",\r\n\t\t\t\t\t\t\t\"negativeLineAlpha\": 0,\r\n\t\t\t\t\t\t\t\"showBalloon\": false,\r\n\t\t\t\t\t\t\t\"switchable\": false,\r\n\t\t\t\t\t\t\t\"title\": \"Pacientes con respuesta\",\r\n\t\t\t\t\t\t\t\"type\": \"column\",\r\n\t\t\t\t\t\t\t\"valueField\": \"column-1\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"accessibleLabel\": \"STELVIO - Cambio en la DR6 - Grupo cruzado con grupo de la v\u00e1lvula Zephyr n =26\",\r\n\t\t\t\t\t\t\t\"balloonText\": \"\",\r\n\t\t\t\t\t\t\t\"id\": \"AmGraph-2\",\r\n\t\t\t\t\t\t\t\"legendColor\": \"#AAB3B3\",\r\n\t\t\t\t\t\t\t\"title\": \"Pacientes sin respuesta\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t],\r\n\t\t\t\t\t\"guides\": [\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"above\": true,\r\n\t\t\t\t\t\t\t\"id\": \"Guide-1\",\r\n\t\t\t\t\t\t\t\"inside\": false,\r\n\t\t\t\t\t\t\t\"label\": \"MCID (26 m)\",\r\n\t\t\t\t\t\t\t\"lineThickness\": 3,\r\n\t\t\t\t\t\t\t\"position\": \"right\",\r\n\t\t\t\t\t\t\t\"value\": 26\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t],\r\n\t\t\t\t\t\"valueAxes\": [\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"id\": \"ValueAxis-1\",\r\n\t\t\t\t\t\t\t\"maximum\": 250,\r\n\t\t\t\t\t\t\t\"minimum\": -150,\r\n\t\t\t\t\t\t\t\"treatZeroAs\": 20,\r\n\t\t\t\t\t\t\t\"autoGridCount\": false,\r\n\t\t\t\t\t\t\t\"gridCount\": 10,\r\n\t\t\t\t\t\t\t\"title\": \"Metros (m)\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t],\r\n\t\t\t\t\t\"allLabels\": [],\r\n\t\t\t\t\t\"balloon\": {\r\n\t\t\t\t\t\t\"borderThickness\": 1\r\n\t\t\t\t\t},\r\n\t\t\t\t\t\"legend\": {\r\n\t\t\t\t\t\t\"enabled\": true,\r\n\t\t\t\t\t\t\"combineLegend\": true,\r\n\t\t\t\t\t\t\"switchable\": false\r\n\t\t\t\t\t},\r\n\t\t\t\t\t\"titles\": [],\r\n\t\t\t\t\t\"dataProvider\": [\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": 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\"#FF5C39\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"\",\r\n\t\t\t\t\t\t\t\"column-1\": \"85\",\r\n\t\t\t\t\t\t\t\"Color\": \"#FF5C39\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"\",\r\n\t\t\t\t\t\t\t\"column-1\": \"106\",\r\n\t\t\t\t\t\t\t\"Color\": \"#FF5C39\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"\",\r\n\t\t\t\t\t\t\t\"column-1\": \"112\",\r\n\t\t\t\t\t\t\t\"Color\": \"#FF5C39\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": null,\r\n\t\t\t\t\t\t\t\"column-1\": \"112\",\r\n\t\t\t\t\t\t\t\"Color\": \"#FF5C39\"\r\n\t\t\t\t\t\t},\r\n\t\t\t\t\t\t{\r\n\t\t\t\t\t\t\t\"category\": \"\",\r\n\t\t\t\t\t\t\t\"column-1\": \"114\",\r\n\t\t\t\t\t\t\t\"Color\": \"#FF5C39\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"spanish-stelvio-6mwd-crossover\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html> <\/div>\n<\/div>\n<!-- \/module plain text --> <\/div>\n <\/div>\n <div data-lazy=\"1\" class=\"module_subrow themify_builder_sub_row tf_w col_align_top tb_col_count_4 tb_4t40589\">\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_ouuy589 first\">\n <!-- module text -->\n<div class=\"module module-text tb_n5mf334 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <p class=\"p1\">Cambio en el CRSG<\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_ye4z590\">\n <!-- module text -->\n<div class=\"module module-text tb_jufa590 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h5 style=\"text-align: center;\">Grupo de control<br>n=33<\/h5> <\/div>\n<\/div>\n<!-- \/module text --><!-- module plain text -->\n<div class=\"module module-plain-text tb_bgw7256 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>STELVIO Study Page - Spanish: STELVIO - SGRQ - Control Group | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" \/>\r\n\t\t\r\n\t\t<!-- amCharts javascript sources -->\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/amcharts.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/cdn.amcharts.com\/lib\/3\/serial.js\"><\/script>\r\n\t\t<script type=\"text\/javascript\" src=\"https:\/\/www.amcharts.com\/lib\/3\/themes\/light.js\"><\/script>\r\n\t\t\r\n\r\n\t\t<!-- amCharts javascript code -->\r\n\t\t<script type=\"text\/javascript\">\r\n\t\t\tAmCharts.makeChart(\"spanish-stelvio-sgrq-control-group\",\r\n\t\t\t\t{\r\n \t\t\"hideCredits\": \"true\",\r\n\t\t\t\t\t\"type\": \"serial\",\r\n\t\t\t\t\t\"categoryField\": \"category\",\r\n\t\t\t\t\t\"autoMarginOffset\": 0,\r\n\t\t\t\t\t\"autoMargins\": false,\r\n\t\t\t\t\t\"marginBottom\": 60,\r\n\t\t\t\t\t\"marginLeft\": 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\"#3095B4\"\r\n\t\t\t\t\t\t}\r\n\t\t\t\t\t]\r\n\t\t\t\t}\r\n\t\t\t);\r\n\t\t<\/script>\r\n\t<\/head>\r\n\t<body>\r\n\t\t<div id=\"spanish-stelvio-sgrq-control-group\" style=\"width: 100%; height: 400px; background-color: #FFFFFF;\" ><\/div>\r\n\t<\/body>\r\n<\/html> <\/div>\n<\/div>\n<!-- \/module plain text --> <\/div>\n <div data-lazy=\"1\" class=\"module_column sub_column col4-1 tb_5re9590\">\n <!-- module text -->\n<div class=\"module module-text tb_86n1590 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h5 style=\"text-align: center;\">Grupo de la v\u00e1lvula Zephyr<br>n=25<\/h5> <\/div>\n<\/div>\n<!-- \/module text --><!-- module plain text -->\n<div class=\"module module-plain-text tb_0oto749 \" data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <!DOCTYPE html>\r\n<html>\r\n\t<head>\r\n\t\t<title>STELVIO Study Page - Spanish: STELVIO - SGRQ - Zephyr Valve | amCharts<\/title>\r\n\t\t<meta name=\"description\" content=\"chart created using amCharts live editor\" 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data-lazy=\"1\">\n <div class=\"tb_text_wrap\">\n <h2 class=\"p1\">Conclusi\u00f3n<\/h2>\n<p class=\"p1\">El tratamiento con v\u00e1lvulas endobronquiales mejor\u00f3 significativamente la funci\u00f3n pulmonar y la capacidad de ejercicio en pacientes con enfisema grave caracterizado por la ausencia de ventilaci\u00f3n colateral interlobar.<\/p>\n<p>Entre las complicaciones del tratamiento con la v\u00e1lvula endobronquial Zephyr, se pueden incluir, entre otras, neumot\u00f3rax, empeoramiento de la sintomatolog\u00eda de EPOC, hemoptisis, neumon\u00eda, disnea y, con escasa incidencia, fallecimiento.<\/p> <\/div>\n<\/div>\n<!-- \/module text --> <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n<!--\/themify_builder_content-->","protected":false},"excerpt":{"rendered":"<p>Ensayo controlado aleatorizado, multinacional y multic\u00e9ntrico de v\u00e1lvulas endobronquiales Zephyr\u00ae en pacientes con enfisema heterog\u00e9neo y poca o ninguna ventilaci\u00f3n colateral.<\/p>\n","protected":false},"author":2,"featured_media":75350,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[51],"tags":[],"class_list":["post-74898","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-evidencia-clinica","has-post-title","has-post-date","has-post-category","has-post-tag","has-post-comment","has-post-author",""],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>STELVIO Estudio cl\u00ednico - Pulmonx<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pulmonx.com\/es\/stelvio-estudio-clinico\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" 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