{"id":101862,"date":"2026-09-14T11:02:43","date_gmt":"2026-09-14T16:02:43","guid":{"rendered":"https:\/\/pulmonx.com\/?page_id=101862"},"modified":"2026-09-14T12:01:16","modified_gmt":"2026-09-14T17:01:16","slug":"persistierender-fisteln","status":"publish","type":"page","link":"https:\/\/pulmonx.com\/de\/persistierender-fisteln\/","title":{"rendered":"Behandlung persistierender Fisteln"},"content":{"rendered":"\n
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Bronchoskopische Behandlung persistierender Fisteln
\nMinimal-invasive Behandlung<\/h1>\n <\/div>\n<\/div>\n
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Persistierende Fisteln (persistent air leak, PAL) in der Lunge dauern per Definition \u00fcber mehr als 5\u20137 Tage an, was zu einer verl\u00e4ngerten Thoraxdrainage und einem l\u00e4ngeren Krankenhausaufenthalt f\u00fchren und die Morbidit\u00e4t erh\u00f6hen kann.1-6<\/sup><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n <\/div>\n<\/div>\n\n

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Zephyr \u00ae<\/sup> Ventile, minimal-invasiv \u00fcber ein Bronchoskop eingesetzt, behandeln persistierende Fisteln effektiv. Sie k\u00f6nnen im Vergleich zur alleinigen Standardbehandlung mit Thoraxdrainage zu einem k\u00fcrzeren Krankenhausaufenthalt f\u00fchren.7<\/sup><\/div>\n<\/div>\n<\/div>\n<\/div>\n <\/div>\n<\/div>\n\n
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Was versteht man unter einer persistierenden Fistel?<\/h1>\n <\/div>\n<\/div>\n
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Bronchialfisteln werden als abnorme Kurzschlussverbindungen zwischen dem Lungengewebe und den umliegenden Strukturen definiert, wodurch ein Pneumothorax entsteht. Die Ursache ist eine alveolopleurale Fistel, eine Verbindung zwischen den Alveolen und dem Pleuraspalt. Die Kurzschlussverbindung kann auch zwischen einem Bronchus und der Pleura auftreten, eine bronchopleurale Fistel.\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n <\/div>\n<\/div>\n\n

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Str\u00f6mt Luft kontinuierlich durch die Fistel in die Pleurah\u00f6hle, kann die Luftansammlung so gro\u00df werden, dass sie die Ausdehnung der Lunge behindert und eine Behandlung mit einer Thoraxdrainage erforderlich wird.1<\/sup><\/div>\n<\/div>\n<\/div>\n<\/div>\n <\/div>\n<\/div>\n\n
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Eine persistierende Fistel h\u00e4lt per Definition \u00fcber einen Zeitraum von mehr als f\u00fcnf bis sieben Tagen an.<\/div>\n<\/div>\n<\/div>\n<\/div>\n <\/div>\n<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n
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Wie werden persistierende Fisteln mit Zephyr Ventilen behandelt?<\/h1>\n <\/div>\n<\/div>\n
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Zephyr Ventile werden \u00fcber ein Bronchoskop, entweder unter Sedierung oder Vollnarkose, eingesetzt.8<\/sup><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n <\/div>\n<\/div>\n\n

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Zephyr Ventile, die in die Lappen- oder Segmentbronchien eingesetzt werden, blockieren den Luftstrom zur Fistel und erm\u00f6glichen so die R\u00fcckbildung des Pneumothorax.\u2028

Fiorelli A et al. haben nachgewiesen, dass 88 % der Fisteln innerhalb von 5,0 Tagen (\u00b11,7 Tage) abheilen.<\/p><\/div><\/div><\/div><\/div> <\/div>\n<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n

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Klinische Evidenz<\/h1>\n <\/div>\n<\/div>\n
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Der Erfolg von Zephyr Ventilen bei der Behandlung persistierender Fisteln wurde in mehreren Fallserien und Fallberichten beschrieben.\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n <\/div>\n<\/div>\n\n

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In einer retrospektiven multizentrischen Studie zur Bewertung von Zephyr Ventilen bei persistierenden Fisteln infolge einer alveolopleuralen Fistel erreichten 88 % der Patienten eine vollst\u00e4ndige Abheilung der Fistel, w\u00e4hrend weitere 9 % eine Verringerung der Schwere der Fistel zeigten.7<\/sup><\/p><\/div><\/div><\/div><\/div> <\/div>\n<\/div>\n\n

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Die Ventile wurden bei 82 % der Patienten nach durchschnittlich 134 \u00b1 83 Tagen entfernt, ohne berichtete Komplikationen oder Rezidive der Fistel nach der Entfernung.7<\/sup><\/div><\/div><\/div><\/div> <\/div>\n<\/div>\n <\/div>\n
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Sehen Sie sich alle Fallstudien an und erfahren Sie mehr \u00fcber die Behandlung persistierender Fisteln mit Zephyr Ventilen in unserer Brosch\u00fcre.<\/div>\n<\/div>\n<\/div>\n<\/div>\n <\/div>\n<\/div>\n
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Das Verfahren \u2013 Schritt f\u00fcr Schritt<\/h1>\n <\/div>\n<\/div>\n
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Wichtige Ergebnisse<\/h1>\n

Effektive Behandlung persistierender Fisteln7<\/sup><\/h4>\n <\/div>\n<\/div>\n
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Literaturangabe<\/strong>
\n1 DuganK et al. (2017) Management of Persistent Air Leaks CHEST 2017; 152(2):417-423
\n2 Sirbu, H, Busch, T, Aleksic, I, Schreiner, W, Oster, O, & Dalichau, H. Bronchopleural fistula in the surgery of non-small cell lung cancer: incidence, risk factors, and management. Ann Thorac Cardiovasc Surg, 2001; 7(6), 330\u2013336.
\n3 Liang, S, et al. Quantifying the incidence and impact of postoperative prolonged alveolar air leak after pulmonary resection. J Thorac Cardiovasc Surg, 2013; 145(4), 948\u2013954.
\n4 Bardell, T, & Petsikas, D. What keeps postpulmonary resection patients in hospital?. Can Respir J, 2003; 10(2), 86-89.
\n5 Varela, Gonzalo, et al. Estimating hospital costs attributable to prolonged air leak in pulmonary lobectomy. Eur J Cardiothorac Surg, 2005; 27(2), 329\u2013333.
\n6 Irshad, Kashif, et al. Causes of increased length of hospitalization on a general thoracic surgery service: a prospective obser-vational study. Can J Surg, 2002; 45(4), 264.
\n7 Fiorelli A, D\u2019Andrilli A, Cascone R, Occhiati L, Anile M, Diso D, Cassiano F, Poggi C,Ibrahim M, Cusumano G, Terminella A, Failla G, La Sala A, Bezzi M, Innocenti M, Torricelli E, Venuta F, Rendina EA, Vicidomini G, Santini M, Andreetti C. Unidi-rectional endobronchial valves for management of persistent air-leaks: results of a multicenter study. J Thorac Dis 2018;10(11):6158-6167. doi: 10.21037\/ jtd.2018.10.61
\n8 Pulmonx Corp. Zephyr\u00ae<\/sup> Endobronchial Valve System Clinical Evaluation Report. Document 631-0016, Revision J. Redwood City, CA: Pulmonx Corporation; 2025; Section 3.7 (Intended Users).
\n9 Mahajan AK, Doeing DC, Hogarth DK. Isolation of persistent air leaks and placement of intrabronchial valves. J Thorac Cardiovasc Surg. 2013;145:626-630
\n10 Ficial, B.; Whebell, S.; Taylor, D.; Fern\u00e1ndez-Garda, R.; Okiror, L.; Meadows, C.I.S. Bronchoscopic Endobronchial Valve Therapy for Persistent Air Leaks in COVID-19 Patients Requiring Veno-Venous Extracorporeal Membrane Oxygenation. J. Clin. Med. 2023, 12, 1348.<\/p>\n

EMEA-DE-2925-v1<\/p>\n <\/div>\n<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n","protected":false},"excerpt":{"rendered":"

Bronchoskopische Behandlung persistierender Fisteln Minimal-invasive Behandlung Persistierende Fisteln (persistent air leak, PAL) in der Lunge dauern per Definition \u00fcber mehr als 5\u20137 Tage an, was zu einer verl\u00e4ngerten Thoraxdrainage und einem l\u00e4ngeren Krankenhausaufenthalt f\u00fchren und die Morbidit\u00e4t erh\u00f6hen kann.1-6 Zephyr \u00ae Ventile, minimal-invasiv \u00fcber ein Bronchoskop eingesetzt, behandeln persistierende Fisteln effektiv. Sie k\u00f6nnen im Vergleich […]<\/p>\n","protected":false},"author":1208,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-101862","page","type-page","status-publish","hentry","has-post-title","has-post-date","has-post-category","has-post-tag","has-post-comment","has-post-author",""],"acf":[],"yoast_head":"\nBehandlung persistierender Fisteln - Pulmonx<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pulmonx.com\/de\/persistierender-fisteln\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Behandlung persistierender Fisteln - Pulmonx\" \/>\n<meta property=\"og:description\" content=\"Bronchoskopische Behandlung persistierender Fisteln Minimal-invasive Behandlung Persistierende Fisteln (persistent air leak, PAL) in der Lunge dauern per Definition \u00fcber mehr als 5\u20137 Tage an, was zu einer verl\u00e4ngerten Thoraxdrainage und einem l\u00e4ngeren Krankenhausaufenthalt f\u00fchren und die Morbidit\u00e4t erh\u00f6hen kann.1-6 Zephyr \u00ae Ventile, minimal-invasiv \u00fcber ein Bronchoskop eingesetzt, behandeln persistierende Fisteln effektiv. 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