Welcome to the Virtual Tour for Referring Pulmonologist & HCPs
Breakthrough Technology for Severe Emphysema
Helping Patients Breathe Easier, Do More, and Enjoy Life
The Zephyr® Valve delivers durable clinical benefits — without surgery and its associated risks.1-5
Patients experience:1-5
- Improved health status
- Improved lung function
- Increased exercise capacity
- Reduced breathlessness or dyspnea
- Reduced gas trapping
- Improved quality of life

Pulmonologist Perspective:
How Zephyr Valves Work
Zephyr Valve Patient Benefits
How It Works
See how the Zephyr Valve treatment is performed as a minimally invasive lung volume reduction procedure to reduce hyperinflation and gas trapping in patients with severe emphysema. The Zephyr Valve is the first endobronchial valve to receive approval from the FDA for patients with either heterogenous or homogeneous emphysema.
Key Patient Selection Criteria
- Confirmed diagnosis of COPD
- Non-smoking or willing to quit smoking
- FEV1≤50% predicted
- Breathless despite optimal medical management (mMRC≥2)
Making a Referral:
Patients who might benefit from Zephyr Valve therapy include
- Patients who are not responding to optimal medical management
- Patients who prefer additional treatment options
Once Referred an Interventional Pulmonologist Will Confirm
- Diagnosis of severe emphysema
- Presence of hyperinflation (RV≥175% predicted)
- Confirmation the target lobe has little to no collateral ventilation
Clinical Evidence
Consistent Clinical Findings Across Four Randomized Controlled Trials
Featured Patient Stories
Charlie’s Story
Age at Treatment: 68
Fairfax, Virginia
My story about this procedure tells people what life can be even with COPD. It really brought me back. I am a walking Christmas present.
Flo’s Story
Age at Treatment: 63
Texas City, TX
I feel strongly that part of my new path in life is to help spread the word about the Zephyr Valves so other sufferers can learn about this option and have hope.
LIBERATE1 Primary & Secondary Endpoints
Primary Endpoint Responder Analysis
Percent of Subjects with FEV1 Change of ≥15%
Secondary Endpoints
Change in St. George’s Resp Questionnaire
Change in FEV1
Change in 6MWD
Zephyr Valve Procedure
Complications of the Zephyr Endobronchial Valve Treatment include but are not limited to pneumothorax, worsening of COPD symptoms, hemoptysis, pneumonia, dyspnea and, in rare cases, death.
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